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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDX4
All Species:
31.82
Human Site:
S253
Identified Species:
50
UniProt:
Q13162
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13162
NP_006397.1
271
30540
S253
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Chimpanzee
Pan troglodytes
XP_001144211
335
37352
S254
P
A
G
W
K
P
G
S
E
T
V
I
H
S
G
Rhesus Macaque
Macaca mulatta
XP_001087492
271
30482
S253
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Dog
Lupus familis
XP_548896
272
30364
S254
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Cat
Felis silvestris
Mouse
Mus musculus
O08807
274
31034
S256
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Rat
Rattus norvegicus
Q9Z0V5
273
30989
S255
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509414
221
24717
E204
A
G
W
K
P
G
S
E
T
I
I
P
D
P
A
Chicken
Gallus gallus
P0CB50
199
22296
D182
A
G
W
K
P
G
S
D
T
I
K
P
D
V
Q
Frog
Xenopus laevis
NP_001088817
268
29936
S250
P
A
G
W
K
P
G
S
E
T
I
I
P
D
P
Zebra Danio
Brachydanio rerio
XP_002661980
260
29093
S242
P
A
G
W
K
P
G
S
D
T
I
I
P
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3P0
194
21719
K177
A
N
W
K
P
G
Q
K
T
M
V
A
D
P
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21824
226
24914
T209
D
W
H
E
D
S
P
T
I
K
P
G
V
A
T
Sea Urchin
Strong. purpuratus
XP_784460
248
27070
N231
V
S
P
S
I
I
P
N
P
A
D
K
L
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C5R8
271
29543
G253
C
P
A
G
W
K
P
G
E
K
S
M
K
P
D
Baker's Yeast
Sacchar. cerevisiae
P34760
196
21571
T179
N
W
T
P
G
A
A
T
I
K
P
T
V
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.6
98.5
92.6
N.A.
89.4
88.6
N.A.
70.1
50.5
80.4
77.8
N.A.
49
N.A.
47.2
69.3
Protein Similarity:
100
78.2
99.2
95.5
N.A.
92.6
92.3
N.A.
76
61.2
85.2
85.9
N.A.
59.7
N.A.
60.8
78.2
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
6.6
0
100
93.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
6.6
0
100
100
N.A.
6.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.2
41.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
60.8
52.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
54
7
0
0
7
7
0
0
7
0
7
0
7
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
7
7
0
7
0
20
47
14
% D
% Glu:
0
0
0
7
0
0
0
7
54
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
54
7
7
20
54
7
0
0
0
7
0
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
14
14
54
54
0
0
0
% I
% Lys:
0
0
0
20
54
7
0
7
0
20
7
7
7
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
54
7
7
7
20
54
20
0
7
0
14
14
47
20
47
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
7
0
7
14
54
0
0
7
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
0
14
20
54
0
7
0
0
14
% T
% Val:
7
0
0
0
0
0
0
0
0
0
14
0
14
7
0
% V
% Trp:
0
14
20
54
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _