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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK7 All Species: 15.15
Human Site: S496 Identified Species: 25.64
UniProt: Q13164 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13164 NP_002740.2 816 88386 S496 S R L R D G P S A P L E A P E
Chimpanzee Pan troglodytes XP_511332 494 55249 Q213 H V R Y F L Y Q L L R G L K Y
Rhesus Macaque Macaca mulatta XP_001099721 816 88521 S496 S R L R D G P S A P L E A S E
Dog Lupus familis XP_546651 731 80417 D450 G P A P D T I D L T L Q P P L
Cat Felis silvestris
Mouse Mus musculus Q9WVS8 806 87714 S496 S R L R D G P S A P L E A P E
Rat Rattus norvegicus P0C865 806 87808 S496 S R L R D G P S A P L E A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518277 258 29416
Chicken Gallus gallus
Frog Xenopus laevis P26696 361 41238 R80 R E I K I L L R F K H E N I I
Zebra Danio Brachydanio rerio NP_001013469 862 94944 S508 S L P Q S V P S L S L S Q S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780133 1079 118303 L666 A K G E A T P L I E E Q I S S
Poplar Tree Populus trichocarpa XP_002302599 372 42612 L91 R T L R E I K L L R H M D H E
Maize Zea mays NP_001152745 397 44917 L116 R T L R E I K L L R H M D H E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39024 376 42833 K95 L R E I K L L K H M D H E N V
Baker's Yeast Sacchar. cerevisiae Q00772 484 55617 I203 R W Y R A P E I M L S Y Q G Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 97.6 86.7 N.A. 92 92.1 N.A. 30.3 N.A. 24.1 47.3 N.A. N.A. N.A. N.A. 32.7
Protein Similarity: 100 54.6 98 87.9 N.A. 93.2 93.3 N.A. 31 N.A. 32.8 59.1 N.A. N.A. N.A. N.A. 46.7
P-Site Identity: 100 0 93.3 20 N.A. 100 100 N.A. 0 N.A. 6.6 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 93.3 26.6 N.A. 100 100 N.A. 0 N.A. 20 40 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: 26.2 26.1 N.A. 25.7 28.8 N.A.
Protein Similarity: 35 35 N.A. 34.6 40.5 N.A.
P-Site Identity: 20 20 N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 15 0 0 0 29 0 0 0 29 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 36 0 0 8 0 0 8 0 15 0 0 % D
% Glu: 0 8 8 8 15 0 8 0 0 8 8 36 8 0 43 % E
% Phe: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 0 29 0 0 0 0 0 8 0 8 0 % G
% His: 8 0 0 0 0 0 0 0 8 0 22 8 0 15 0 % H
% Ile: 0 0 8 8 8 15 8 8 8 0 0 0 8 8 8 % I
% Lys: 0 8 0 8 8 0 15 8 0 8 0 0 0 8 0 % K
% Leu: 8 8 43 0 0 22 15 22 36 15 43 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 15 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % N
% Pro: 0 8 8 8 0 8 43 0 0 29 0 0 8 29 0 % P
% Gln: 0 0 0 8 0 0 0 8 0 0 0 15 15 0 8 % Q
% Arg: 29 36 8 50 0 0 0 8 0 15 8 0 0 0 0 % R
% Ser: 36 0 0 0 8 0 0 36 0 8 8 8 0 22 8 % S
% Thr: 0 15 0 0 0 15 0 0 0 8 0 0 0 0 0 % T
% Val: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 8 0 0 0 0 8 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _