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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK7 All Species: 12.73
Human Site: T452 Identified Species: 21.54
UniProt: Q13164 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13164 NP_002740.2 816 88386 T452 A P D T I D L T L Q P P P P V
Chimpanzee Pan troglodytes XP_511332 494 55249 L169 I I A I K D I L R P T V P Y G
Rhesus Macaque Macaca mulatta XP_001099721 816 88521 T452 G P D T I D L T L Q P P P P A
Dog Lupus familis XP_546651 731 80417 Q406 I R F Q P S L Q P V A S E P G
Cat Felis silvestris
Mouse Mus musculus Q9WVS8 806 87714 T452 A P D T V D L T L Q P A P P A
Rat Rattus norvegicus P0C865 806 87808 T452 A P D T V D L T L Q P A P P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518277 258 29416
Chicken Gallus gallus
Frog Xenopus laevis P26696 361 41238 E36 I N L A Y I G E G A Y G M V C
Zebra Danio Brachydanio rerio NP_001013469 862 94944 T464 T I D L T T P T D K D T S F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780133 1079 118303 D622 S A K S T S G D P L T S F F M
Poplar Tree Populus trichocarpa XP_002302599 372 42612 V47 Y V P P I R P V G R G A Y G I
Maize Zea mays NP_001152745 397 44917 I72 Y K P P I L P I G K G A Y G I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39024 376 42833 R51 P P L R P I G R G A Y G I V C
Baker's Yeast Sacchar. cerevisiae Q00772 484 55617 L159 R D L K P G N L L V N A D C Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 97.6 86.7 N.A. 92 92.1 N.A. 30.3 N.A. 24.1 47.3 N.A. N.A. N.A. N.A. 32.7
Protein Similarity: 100 54.6 98 87.9 N.A. 93.2 93.3 N.A. 31 N.A. 32.8 59.1 N.A. N.A. N.A. N.A. 46.7
P-Site Identity: 100 13.3 86.6 13.3 N.A. 80 80 N.A. 0 N.A. 0 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 20 86.6 13.3 N.A. 86.6 86.6 N.A. 0 N.A. 0 20 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 26.2 26.1 N.A. 25.7 28.8 N.A.
Protein Similarity: 35 35 N.A. 34.6 40.5 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 6.6 N.A.
P-Site Similarity: 20 20 N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 8 8 0 0 0 0 0 15 8 36 0 0 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 15 % C
% Asp: 0 8 36 0 0 36 0 8 8 0 8 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 8 15 0 % F
% Gly: 8 0 0 0 0 8 22 0 29 0 15 15 0 15 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 15 0 8 29 15 8 8 0 0 0 0 8 0 15 % I
% Lys: 0 8 8 8 8 0 0 0 0 15 0 0 0 0 0 % K
% Leu: 0 0 22 8 0 8 36 15 36 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 0 8 0 0 0 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 8 36 15 15 22 0 22 0 15 8 29 15 36 36 0 % P
% Gln: 0 0 0 8 0 0 0 8 0 29 0 0 0 0 8 % Q
% Arg: 8 8 0 8 0 8 0 8 8 8 0 0 0 0 0 % R
% Ser: 8 0 0 8 0 15 0 0 0 0 0 15 8 0 0 % S
% Thr: 8 0 0 29 15 8 0 36 0 0 15 8 0 0 8 % T
% Val: 0 8 0 0 15 0 0 8 0 15 0 8 0 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 8 0 0 0 0 0 15 0 15 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _