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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK2
All Species:
9.09
Human Site:
T178
Identified Species:
16.67
UniProt:
Q13177
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13177
NP_002568.2
524
58043
T178
E
E
D
D
D
E
E
T
A
P
P
V
I
A
P
Chimpanzee
Pan troglodytes
XP_516976
524
58004
T178
E
E
D
D
D
E
E
T
A
P
P
V
I
A
P
Rhesus Macaque
Macaca mulatta
XP_001099936
524
57950
T178
E
D
D
D
D
E
E
T
A
P
P
V
I
A
P
Dog
Lupus familis
XP_849432
524
57951
A178
E
D
D
D
D
E
E
A
A
P
P
V
I
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIN4
524
57912
A178
E
D
D
D
D
E
D
A
A
P
P
V
I
A
P
Rat
Rattus norvegicus
Q64303
524
57942
A178
E
D
D
D
D
E
D
A
A
P
P
V
I
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422671
521
57527
A175
D
D
D
D
D
E
E
A
P
P
P
I
I
A
P
Frog
Xenopus laevis
NP_001083738
517
57265
A173
D
D
F
D
D
D
K
A
P
P
P
A
I
A
P
Zebra Danio
Brachydanio rerio
NP_001020627
539
59696
P193
D
D
D
E
E
T
P
P
P
V
V
A
P
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
H297
N
Q
N
P
L
H
P
H
A
H
P
H
P
H
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
A224
V
P
H
G
E
T
P
A
D
I
V
P
P
A
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
I549
T
K
S
K
T
S
P
I
I
S
T
A
H
T
P
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
A603
M
S
G
Q
L
S
R
A
A
S
K
R
Q
Q
P
Conservation
Percent
Protein Identity:
100
99.6
99
96.7
N.A.
97.1
96.9
N.A.
N.A.
92.7
87.2
83.8
N.A.
34.4
N.A.
53.3
N.A.
Protein Similarity:
100
99.6
99.2
98.2
N.A.
98.4
98.2
N.A.
N.A.
95.6
92.5
89
N.A.
50.5
N.A.
68.5
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
N.A.
66.6
46.6
13.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
73.3
40
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32
32.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.4
42.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
54
62
0
0
24
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
54
62
62
62
8
16
0
8
0
0
0
0
0
0
% D
% Glu:
47
16
0
8
16
54
39
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
8
0
8
0
8
0
8
8
8
8
% H
% Ile:
0
0
0
0
0
0
0
8
8
8
0
8
62
0
8
% I
% Lys:
0
8
0
8
0
0
8
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
31
8
24
62
70
8
24
0
85
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% R
% Ser:
0
8
8
0
0
16
0
0
0
16
0
0
0
0
0
% S
% Thr:
8
0
0
0
8
16
0
24
0
0
8
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
16
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _