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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC13A2 All Species: 6.36
Human Site: S166 Identified Species: 11.67
UniProt: Q13183 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13183 NP_001139447.1 592 64410 S166 L H S S Q A S S N V E E G S N
Chimpanzee Pan troglodytes XP_001146374 592 64418 S166 L H S S Q A S S N V E E G S N
Rhesus Macaque Macaca mulatta XP_001106342 566 61315 D163 P I A H A V L D Q L H S S Q A
Dog Lupus familis XP_548287 591 64717 K164 E Q L H N T S K D V E E G S D
Cat Felis silvestris
Mouse Mus musculus Q9ES88 586 64092 G161 A V L E Q L Q G S Q K D V E E
Rat Rattus norvegicus P70545 587 64188 A160 A V L E Q L Q A S K K D V E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507053 642 69742 S212 E E G T V N H S F E L Q E P V
Chicken Gallus gallus XP_425404 584 64537 F173 S E A A N Q V F E N D N K A F
Frog Xenopus laevis NP_001079286 622 68519 Y205 A L A I D D T Y A T E N E G F
Zebra Danio Brachydanio rerio NP_998617 613 67635 V181 K E L R E G Q V N Q A F E L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVT2 590 65567 A171 L S M W I S N A A C T A M M C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93655 582 64168 H169 I T E L V S N H R M E D L V A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LG88 540 58080 F131 I S L V L G S F I L A L A V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 80.9 80.9 N.A. 76.6 75.1 N.A. 65.5 63.3 61.4 59.5 N.A. 37.5 N.A. 40 N.A.
Protein Similarity: 100 99.3 85.8 89.6 N.A. 87.8 85.9 N.A. 76.9 77.8 76.2 76 N.A. 61.3 N.A. 58.2 N.A.
P-Site Identity: 100 100 0 40 N.A. 6.6 6.6 N.A. 6.6 0 6.6 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 13.3 53.3 N.A. 26.6 33.3 N.A. 20 26.6 20 13.3 N.A. 26.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 24 8 8 16 0 16 16 0 16 8 8 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % C
% Asp: 0 0 0 0 8 8 0 8 8 0 8 24 0 0 8 % D
% Glu: 16 24 8 16 8 0 0 0 8 8 39 24 24 16 16 % E
% Phe: 0 0 0 0 0 0 0 16 8 0 0 8 0 0 16 % F
% Gly: 0 0 8 0 0 16 0 8 0 0 0 0 24 8 8 % G
% His: 0 16 0 16 0 0 8 8 0 0 8 0 0 0 0 % H
% Ile: 16 8 0 8 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 8 0 8 16 0 8 0 0 % K
% Leu: 24 8 39 8 8 16 8 0 0 16 8 8 8 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 8 0 0 8 8 0 % M
% Asn: 0 0 0 0 16 8 16 0 24 8 0 16 0 0 16 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 0 31 8 24 0 8 16 0 8 0 8 0 % Q
% Arg: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % R
% Ser: 8 16 16 16 0 16 31 24 16 0 0 8 8 24 0 % S
% Thr: 0 8 0 8 0 8 8 0 0 8 8 0 0 0 8 % T
% Val: 0 16 0 8 16 8 8 8 0 24 0 0 16 16 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _