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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC13A2 All Species: 11.52
Human Site: T176 Identified Species: 21.11
UniProt: Q13183 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13183 NP_001139447.1 592 64410 T176 E E G S N N P T F E L Q E P S
Chimpanzee Pan troglodytes XP_001146374 592 64418 T176 E E G S N N P T F E L Q E P S
Rhesus Macaque Macaca mulatta XP_001106342 566 61315 N173 H S S Q A S S N L E E G S N N
Dog Lupus familis XP_548287 591 64717 T174 E E G S D N P T F E L Q E G S
Cat Felis silvestris
Mouse Mus musculus Q9ES88 586 64092 S171 K D V E E G N S N P S F E L Q
Rat Rattus norvegicus P70545 587 64188 N170 K D V E G G N N N P T F E L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507053 642 69742 T222 L Q E P V E R T P E K E A P V
Chicken Gallus gallus XP_425404 584 64537 Q183 D N K A F E L Q E E P T K S N
Frog Xenopus laevis NP_001079286 622 68519 Q215 E N E G F E I Q E K S T K D P
Zebra Danio Brachydanio rerio NP_998617 613 67635 N191 A F E L T E V N I K Q P L D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVT2 590 65567 I181 T A M M C P I I Q A V L E E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93655 582 64168 E179 E D L V A L C E A H H N S S R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LG88 540 58080 N141 A L A V E H Y N I H R R L A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 80.9 80.9 N.A. 76.6 75.1 N.A. 65.5 63.3 61.4 59.5 N.A. 37.5 N.A. 40 N.A.
Protein Similarity: 100 99.3 85.8 89.6 N.A. 87.8 85.9 N.A. 76.9 77.8 76.2 76 N.A. 61.3 N.A. 58.2 N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 6.6 6.6 N.A. 20 6.6 6.6 0 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 20 93.3 N.A. 26.6 20 N.A. 33.3 33.3 20 13.3 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 8 8 16 0 0 0 8 8 0 0 8 8 0 % A
% Cys: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 24 0 0 8 0 0 0 0 0 0 0 0 16 0 % D
% Glu: 39 24 24 16 16 31 0 8 16 47 8 8 47 8 0 % E
% Phe: 0 8 0 0 16 0 0 0 24 0 0 16 0 0 0 % F
% Gly: 0 0 24 8 8 16 0 0 0 0 0 8 0 8 0 % G
% His: 8 0 0 0 0 8 0 0 0 16 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 16 8 16 0 0 0 0 0 0 % I
% Lys: 16 0 8 0 0 0 0 0 0 16 8 0 16 0 0 % K
% Leu: 8 8 8 8 0 8 8 0 8 0 24 8 16 16 16 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 0 16 24 16 31 16 0 0 8 0 8 24 % N
% Pro: 0 0 0 8 0 8 24 0 8 16 8 8 0 24 8 % P
% Gln: 0 8 0 8 0 0 0 16 8 0 8 24 0 0 16 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 8 % R
% Ser: 0 8 8 24 0 8 8 8 0 0 16 0 16 16 24 % S
% Thr: 8 0 0 0 8 0 0 31 0 0 8 16 0 0 0 % T
% Val: 0 0 16 16 8 0 8 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _