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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC13A2
All Species:
35.45
Human Site:
T449
Identified Species:
65
UniProt:
Q13183
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13183
NP_001139447.1
592
64410
T449
E
W
L
G
N
K
L
T
P
L
Q
S
V
P
A
Chimpanzee
Pan troglodytes
XP_001146374
592
64418
T449
E
W
L
G
N
K
L
T
P
L
Q
S
V
P
A
Rhesus Macaque
Macaca mulatta
XP_001106342
566
61315
T423
E
W
L
G
N
K
L
T
P
L
Q
S
V
P
T
Dog
Lupus familis
XP_548287
591
64717
T447
E
W
L
G
D
K
L
T
P
L
Q
N
V
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES88
586
64092
T444
K
W
L
G
D
K
L
T
P
L
Q
H
V
P
P
Rat
Rattus norvegicus
P70545
587
64188
T444
E
W
L
G
D
K
L
T
P
L
Q
H
I
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507053
642
69742
T502
S
W
L
G
Y
K
L
T
P
L
Q
N
I
P
P
Chicken
Gallus gallus
XP_425404
584
64537
T456
G
W
L
G
T
K
L
T
P
L
E
N
I
P
H
Frog
Xenopus laevis
NP_001079286
622
68519
T493
L
W
L
G
E
K
L
T
P
L
Q
S
I
P
P
Zebra Danio
Brachydanio rerio
NP_998617
613
67635
S479
V
W
L
G
Q
S
L
S
P
L
K
S
I
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVT2
590
65567
I453
K
L
I
G
N
A
L
I
G
L
K
V
L
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93655
582
64168
R433
H
D
I
G
A
I
M
R
Y
L
D
V
F
N
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LG88
540
58080
P389
W
N
K
C
K
K
L
P
W
N
I
V
L
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
80.9
80.9
N.A.
76.6
75.1
N.A.
65.5
63.3
61.4
59.5
N.A.
37.5
N.A.
40
N.A.
Protein Similarity:
100
99.3
85.8
89.6
N.A.
87.8
85.9
N.A.
76.9
77.8
76.2
76
N.A.
61.3
N.A.
58.2
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
66.6
60
73.3
53.3
N.A.
33.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
86.6
N.A.
80
80
80
73.3
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
16
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
24
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
39
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
93
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
16
0
0
16
% H
% Ile:
0
0
16
0
0
8
0
8
0
0
8
0
39
0
0
% I
% Lys:
16
0
8
0
8
77
0
0
0
0
16
0
0
0
0
% K
% Leu:
8
8
77
0
0
0
93
0
0
93
0
0
16
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
31
0
0
0
0
8
0
24
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
8
77
0
0
0
0
85
39
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
62
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
8
0
0
0
39
0
0
8
% S
% Thr:
0
0
0
0
8
0
0
70
0
0
0
0
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
24
39
0
0
% V
% Trp:
8
77
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _