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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX5 All Species: 24.85
Human Site: S34 Identified Species: 49.7
UniProt: Q13190 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13190 NP_003155.2 355 39673 S34 S P A T A G S S S S D I A P L
Chimpanzee Pan troglodytes XP_508504 355 39635 S34 S P A T A G S S S S D I A P L
Rhesus Macaque Macaca mulatta XP_001116025 355 39620 S34 S P A P A G S S S S D I A P L
Dog Lupus familis XP_853496 355 39614 S34 S P A T A G S S S S D I A P L
Cat Felis silvestris
Mouse Mus musculus Q8K1E0 355 39695 S34 S P A T A I S S S S D S T P L
Rat Rattus norvegicus Q08851 355 39732 S34 S P A T A I N S S S D I A P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24509 467 51832 Y140 I P T S S Q F Y Q S K E E P Q
Honey Bee Apis mellifera XP_624500 364 41154 G43 S S N H E S E G C D L T Q N S
Nematode Worm Caenorhab. elegans Q20797 413 45834 V87 D A D R S K V V E T L E S L S
Sea Urchin Strong. purpuratus XP_001178551 365 41341 V35 Q Q R S G W T V T T H I P P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LK09 347 39100 N36 A P A P A A N N V P Y G N N R
Baker's Yeast Sacchar. cerevisiae Q01590 340 38789 T44 S E N F A N N T T G N G K S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.4 98 N.A. 94 94.9 N.A. N.A. N.A. N.A. N.A. N.A. 43.4 49.4 36.7 55.3
Protein Similarity: 100 99.7 99.4 98.8 N.A. 96.3 96.9 N.A. N.A. N.A. N.A. N.A. N.A. 58.8 69.2 55.6 72.6
P-Site Identity: 100 100 93.3 100 N.A. 80 86.6 N.A. N.A. N.A. N.A. N.A. N.A. 20 6.6 0 13.3
P-Site Similarity: 100 100 93.3 100 N.A. 80 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 33.3 6.6 20 40
Percent
Protein Identity: N.A. N.A. N.A. 23.1 23.1 N.A.
Protein Similarity: N.A. N.A. N.A. 41.9 42.2 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 59 0 67 9 0 0 0 0 0 0 42 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 9 50 0 0 0 0 % D
% Glu: 0 9 0 0 9 0 9 0 9 0 0 17 9 0 9 % E
% Phe: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 34 0 9 0 9 0 17 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 0 17 0 0 0 0 0 50 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 9 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 17 0 0 9 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 0 0 9 25 9 0 0 9 0 9 17 0 % N
% Pro: 0 67 0 17 0 0 0 0 0 9 0 0 9 67 0 % P
% Gln: 9 9 0 0 0 9 0 0 9 0 0 0 9 0 9 % Q
% Arg: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 67 9 0 17 17 9 42 50 50 59 0 9 9 9 17 % S
% Thr: 0 0 9 42 0 0 9 9 17 17 0 9 9 0 0 % T
% Val: 0 0 0 0 0 0 9 17 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _