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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX5
All Species:
38.18
Human Site:
Y265
Identified Species:
76.36
UniProt:
Q13190
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13190
NP_003155.2
355
39673
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Chimpanzee
Pan troglodytes
XP_508504
355
39635
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Rhesus Macaque
Macaca mulatta
XP_001116025
355
39620
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Dog
Lupus familis
XP_853496
355
39614
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1E0
355
39695
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Rat
Rattus norvegicus
Q08851
355
39732
Y265
L
I
D
E
Q
D
S
Y
I
Q
S
R
A
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24509
467
51832
Y377
I
Y
D
D
S
D
N
Y
V
Q
Q
R
A
E
T
Honey Bee
Apis mellifera
XP_624500
364
41154
Y274
V
Q
D
D
T
D
A
Y
V
Q
S
R
A
E
T
Nematode Worm
Caenorhab. elegans
Q20797
413
45834
Y323
Q
R
D
S
S
L
E
Y
A
Q
A
R
S
N
T
Sea Urchin
Strong. purpuratus
XP_001178551
365
41341
Y275
M
V
E
Q
Q
D
N
Y
I
K
N
R
E
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LK09
347
39100
T267
G
R
A
E
A
L
H
T
V
E
S
T
I
H
E
Baker's Yeast
Sacchar. cerevisiae
Q01590
340
38789
L272
T
I
Q
E
V
G
N
L
F
Q
Q
L
A
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
98
N.A.
94
94.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
43.4
49.4
36.7
55.3
Protein Similarity:
100
99.7
99.4
98.8
N.A.
96.3
96.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
58.8
69.2
55.6
72.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
53.3
33.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
80
86.6
53.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
42.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
9
0
9
0
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
75
17
0
75
0
0
0
0
0
0
0
50
0
% D
% Glu:
0
0
9
67
0
0
9
0
0
9
0
0
9
25
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
9
59
0
0
0
0
0
0
59
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
50
0
0
0
0
17
0
9
0
0
0
9
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
25
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
9
9
59
0
0
0
0
84
17
0
0
0
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
84
0
0
0
% R
% Ser:
0
0
0
9
17
0
50
0
0
0
67
0
9
9
0
% S
% Thr:
9
0
0
0
9
0
0
9
0
0
0
9
0
0
84
% T
% Val:
9
9
0
0
9
0
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _