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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBLB All Species: 21.82
Human Site: S503 Identified Species: 43.64
UniProt: Q13191 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13191 NP_733762.2 982 109450 S503 P L Q I P H L S L P P V P P R
Chimpanzee Pan troglodytes XP_516635 1146 126748 I707 P Q P D P L Q I P H L S L P P
Rhesus Macaque Macaca mulatta XP_001104812 907 99834 S493 F S M A P Q A S L P P V P P R
Dog Lupus familis XP_545087 983 109532 S503 P L Q I P H L S L P P V P P R
Cat Felis silvestris
Mouse Mus musculus Q3TTA7 982 109104 S503 P L Q I P H L S L P P V P P R
Rat Rattus norvegicus Q8K4S7 938 104634 I499 P Q P D P L Q I P H L S L P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514020 982 109224 S503 P L Q I P H L S L P P V P P R
Chicken Gallus gallus XP_416621 973 108798 S496 P L Q I P H L S L P P V P P R
Frog Xenopus laevis Q6GQL0 918 102813 P504 S Q R R K T P P E P L Q I P H
Zebra Danio Brachydanio rerio XP_001921961 939 105541 P493 T A A D H M G P H L N I P P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648224 878 94769 A455 D I G D F N I A T S S L H A L
Honey Bee Apis mellifera XP_395448 739 83094 Y326 Y R E G F Y L Y P D G R N I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.7 49.4 97 N.A. 95.1 91.1 N.A. 89.9 85.9 71.8 67.6 N.A. 40.7 42.8 N.A. N.A.
Protein Similarity: 100 81.7 61.5 98.2 N.A. 97 93 N.A. 94.3 90.9 79.1 76.3 N.A. 55 54.7 N.A. N.A.
P-Site Identity: 100 20 60 100 N.A. 100 20 N.A. 100 100 13.3 13.3 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 20 60 100 N.A. 100 20 N.A. 100 100 20 20 N.A. 33.3 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 0 0 9 9 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 34 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % E
% Phe: 9 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 0 9 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 9 42 0 0 9 17 0 0 9 0 9 % H
% Ile: 0 9 0 42 0 0 9 17 0 0 0 9 9 9 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 42 0 0 0 17 50 0 50 9 25 9 17 0 9 % L
% Met: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 9 0 9 0 9 % N
% Pro: 59 0 17 0 67 0 9 17 25 59 50 0 59 84 17 % P
% Gln: 0 25 42 0 0 9 17 0 0 0 0 9 0 0 0 % Q
% Arg: 0 9 9 9 0 0 0 0 0 0 0 9 0 0 50 % R
% Ser: 9 9 0 0 0 0 0 50 0 9 9 17 0 0 0 % S
% Thr: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _