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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBLB All Species: 17.27
Human Site: S583 Identified Species: 34.55
UniProt: Q13191 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13191 NP_733762.2 982 109450 S583 H H V E S V P S R D P P M P L
Chimpanzee Pan troglodytes XP_516635 1146 126748 R760 P A P P P P L R D P P P P P P
Rhesus Macaque Macaca mulatta XP_001104812 907 99834 P546 T L R D L P P P P P P D R P Y
Dog Lupus familis XP_545087 983 109532 S583 H H V E S V P S R D Q P M P L
Cat Felis silvestris
Mouse Mus musculus Q3TTA7 982 109104 S582 H H G E S V P S R D Q P M P L
Rat Rattus norvegicus Q8K4S7 938 104634 R552 P A P P P P L R D P P P P P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514020 982 109224 S583 H H P E S V P S R D L P M P L
Chicken Gallus gallus XP_416621 973 108798 S576 H H P E S V P S R D Q P M P L
Frog Xenopus laevis Q6GQL0 918 102813 P557 Q D K P L P A P P P L L R E P
Zebra Danio Brachydanio rerio XP_001921961 939 105541 E549 P P P P P P P E R P P H L P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648224 878 94769 S509 T P T L S L P S S S C S S I A
Honey Bee Apis mellifera XP_395448 739 83094 R379 A E N D K D V R I E P C G H L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.7 49.4 97 N.A. 95.1 91.1 N.A. 89.9 85.9 71.8 67.6 N.A. 40.7 42.8 N.A. N.A.
Protein Similarity: 100 81.7 61.5 98.2 N.A. 97 93 N.A. 94.3 90.9 79.1 76.3 N.A. 55 54.7 N.A. N.A.
P-Site Identity: 100 20 20 93.3 N.A. 86.6 20 N.A. 86.6 86.6 0 26.6 N.A. 20 13.3 N.A. N.A.
P-Site Similarity: 100 20 26.6 93.3 N.A. 86.6 20 N.A. 86.6 86.6 0 33.3 N.A. 26.6 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 0 0 0 9 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % C
% Asp: 0 9 0 17 0 9 0 0 17 42 0 9 0 0 0 % D
% Glu: 0 9 0 42 0 0 0 9 0 9 0 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 42 42 0 0 0 0 0 0 0 0 0 9 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % I
% Lys: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 9 17 9 17 0 0 0 17 9 9 0 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 25 17 42 34 25 42 67 17 17 42 50 59 17 75 17 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 25 0 0 0 9 % Q
% Arg: 0 0 9 0 0 0 0 25 50 0 0 0 17 0 0 % R
% Ser: 0 0 0 0 50 0 0 50 9 9 0 9 9 0 0 % S
% Thr: 17 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 17 0 0 42 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _