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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMD2 All Species: 40.61
Human Site: S474 Identified Species: 68.72
UniProt: Q13200 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13200 NP_002799.3 908 100200 S474 S D Y V L H N S N T M R L G S
Chimpanzee Pan troglodytes XP_001147451 912 100584 S478 S D Y V L H N S N T M R L G S
Rhesus Macaque Macaca mulatta XP_001093407 991 108053 S599 S D Y V L H N S N T M R L G S
Dog Lupus familis XP_535824 980 107842 S546 S D Y V L H N S N T M R L G S
Cat Felis silvestris
Mouse Mus musculus Q8VDM4 908 100184 S474 S D Y V L H N S N T M R L G S
Rat Rattus norvegicus Q4FZT9 908 100169 S474 S D Y V L H N S N T M R L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012952 908 99980 S474 S D Y V L H N S N T M R I G A
Frog Xenopus laevis NP_001084631 897 99327 S467 S D Y V L H N S N T M R I G A
Zebra Danio Brachydanio rerio NP_956840 897 99460 S464 S D Y V L H N S N I M R I G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649158 919 102259 N470 S D Y I D N Q N S C M R V G A
Honey Bee Apis mellifera XP_624301 892 98607 S455 S D Y V L H S S N T M R I G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793302 773 85625 N398 L L A C G I V N S G V R N E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38764 993 109474 D482 Q D Y V T N P D T K I S S A A
Red Bread Mold Neurospora crassa Q7S8R8 902 100233 N482 P D K L A H K N P L I R V A T
Conservation
Percent
Protein Identity: 100 99.5 85.4 91.9 N.A. 98.6 98.5 N.A. N.A. 93.1 91 89.2 N.A. 62 70.4 N.A. 63.1
Protein Similarity: 100 99.5 86.2 92 N.A. 98.7 98.9 N.A. N.A. 96.4 96 95 N.A. 79.3 83 N.A. 74.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 86.6 80 N.A. 40 80 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 80 100 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 42.2 49.2
Protein Similarity: N.A. N.A. N.A. N.A. 62.2 71
P-Site Identity: N.A. N.A. N.A. N.A. 20 20
P-Site Similarity: N.A. N.A. N.A. N.A. 40 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 0 0 0 0 0 0 0 15 43 % A
% Cys: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 8 % C
% Asp: 0 93 0 0 8 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 8 0 0 0 79 0 % G
% His: 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 8 15 0 29 0 0 % I
% Lys: 0 0 8 0 0 0 8 0 0 8 0 0 0 0 0 % K
% Leu: 8 8 0 8 72 0 0 0 0 8 0 0 43 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 79 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 65 22 72 0 0 0 8 0 0 % N
% Pro: 8 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 % R
% Ser: 79 0 0 0 0 0 8 72 15 0 0 8 8 0 43 % S
% Thr: 0 0 0 0 8 0 0 0 8 65 0 0 0 0 8 % T
% Val: 0 0 0 79 0 0 8 0 0 0 8 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _