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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX10 All Species: 36.67
Human Site: S259 Identified Species: 62.05
UniProt: Q13206 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13206 NP_004389.2 875 100888 S259 F S A T Q T K S V K D L A R L
Chimpanzee Pan troglodytes XP_001141618 875 100804 S259 F S A T Q T K S V K D L A R L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536583 871 100167 S259 F S A T Q T K S V K D L A R L
Cat Felis silvestris
Mouse Mus musculus Q80Y44 875 100720 S259 F S A T Q T K S V K D L A R L
Rat Rattus norvegicus NP_001100290 874 101001 S259 F S A T Q T K S V K D L A R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509692 859 98483 S256 F S A T Q T K S V K D L A R L
Chicken Gallus gallus Q5ZJF6 875 100138 S263 F S A T Q T K S V K D L A R L
Frog Xenopus laevis NP_001089088 663 75544 S153 G L G V L I I S P T R E L A Y
Zebra Danio Brachydanio rerio XP_001922220 864 99178 S260 F S A T Q T R S V K D L A R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573230 826 92827 G278 L K D P V Y V G Y G G A T P R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780056 867 98194 S252 F S A T Q T K S V R D L A R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FFT9 739 83563 R229 L I L D E A D R V L D S A F K
Baker's Yeast Sacchar. cerevisiae P20448 770 87174 R237 Q S V A D L A R L S L T D Y K
Red Bread Mold Neurospora crassa Q7RZ35 823 92654 R247 F S A T Q S K R V S D L A R L
Conservation
Percent
Protein Identity: 100 99 N.A. 89 N.A. 85.1 86.2 N.A. 73.1 66.8 54.1 59.6 N.A. 42.2 N.A. N.A. 48.4
Protein Similarity: 100 99.7 N.A. 94.2 N.A. 92.4 93.1 N.A. 84 79.6 64.2 76.5 N.A. 62.2 N.A. N.A. 68.5
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 6.6 93.3 N.A. 0 N.A. N.A. 93.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 6.6 100 N.A. 0 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. 36.9 38.7 40.2
Protein Similarity: N.A. N.A. N.A. 57.6 56.9 57.7
P-Site Identity: N.A. N.A. N.A. 20 6.6 80
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 86.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 72 8 0 8 8 0 0 0 0 8 79 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 0 8 0 0 0 79 0 8 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 72 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 0 8 0 0 0 0 8 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 65 0 0 58 0 0 0 0 15 % K
% Leu: 15 8 8 0 8 8 0 0 8 8 8 72 8 0 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 8 0 0 0 0 8 0 % P
% Gln: 8 0 0 0 72 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 22 0 8 8 0 0 72 8 % R
% Ser: 0 79 0 0 0 8 0 72 0 15 0 8 0 0 0 % S
% Thr: 0 0 0 72 0 65 0 0 0 8 0 8 8 0 0 % T
% Val: 0 0 8 8 8 0 8 0 79 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _