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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX10 All Species: 14.85
Human Site: S606 Identified Species: 25.13
UniProt: Q13206 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13206 NP_004389.2 875 100888 S606 A K G S Q A P S L P N T S E A
Chimpanzee Pan troglodytes XP_001141618 875 100804 S606 A K G S Q A P S L P N T S E A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536583 871 100167 S603 A K E S Q P Q S V P L T G E A
Cat Felis silvestris
Mouse Mus musculus Q80Y44 875 100720 S606 A R E P H T E S V V S I E E A
Rat Rattus norvegicus NP_001100290 874 101001 S605 T R E P P T D S V P R S E E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509692 859 98483 S603 A Q S E Q V R S V Q F L A Q D
Chicken Gallus gallus Q5ZJF6 875 100138 R614 K E G A L S S R V P Y T N S M
Frog Xenopus laevis NP_001089088 663 75544 P450 I N E I K I N P E K L L D V Q
Zebra Danio Brachydanio rerio XP_001922220 864 99178 N596 L S L L C G F N E E D D D D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573230 826 92827 K589 D E D F I K V K R K D H D V E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780056 867 98194 G590 G D G E G A Y G F H D D A D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FFT9 739 83563 Y526 K T K K K G V Y E S S I A M E
Baker's Yeast Sacchar. cerevisiae P20448 770 87174 L551 T I L S E H Y L N I T K A Q A
Red Bread Mold Neurospora crassa Q7RZ35 823 92654 D590 D D D A A L D D A A G N A K S
Conservation
Percent
Protein Identity: 100 99 N.A. 89 N.A. 85.1 86.2 N.A. 73.1 66.8 54.1 59.6 N.A. 42.2 N.A. N.A. 48.4
Protein Similarity: 100 99.7 N.A. 94.2 N.A. 92.4 93.1 N.A. 84 79.6 64.2 76.5 N.A. 62.2 N.A. N.A. 68.5
P-Site Identity: 100 100 N.A. 60 N.A. 26.6 26.6 N.A. 20 20 0 0 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 66.6 N.A. 46.6 46.6 N.A. 46.6 53.3 6.6 20 N.A. 13.3 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 36.9 38.7 40.2
Protein Similarity: N.A. N.A. N.A. 57.6 56.9 57.7
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 20 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 0 0 15 8 22 0 0 8 8 0 0 36 0 43 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 15 15 0 0 0 15 8 0 0 22 15 22 15 15 % D
% Glu: 0 15 29 15 8 0 8 0 22 8 0 0 15 36 22 % E
% Phe: 0 0 0 8 0 0 8 0 8 0 8 0 0 0 0 % F
% Gly: 8 0 29 0 8 15 0 8 0 0 8 0 8 0 0 % G
% His: 0 0 0 0 8 8 0 0 0 8 0 8 0 0 0 % H
% Ile: 8 8 0 8 8 8 0 0 0 8 0 15 0 0 0 % I
% Lys: 15 22 8 8 15 8 0 8 0 15 0 8 0 8 0 % K
% Leu: 8 0 15 8 8 8 0 8 15 0 15 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 0 8 0 0 0 0 8 8 8 0 15 8 8 0 0 % N
% Pro: 0 0 0 15 8 8 15 8 0 36 0 0 0 0 0 % P
% Gln: 0 8 0 0 29 0 8 0 0 8 0 0 0 15 8 % Q
% Arg: 0 15 0 0 0 0 8 8 8 0 8 0 0 0 0 % R
% Ser: 0 8 8 29 0 8 8 43 0 8 15 8 15 8 8 % S
% Thr: 15 8 0 0 0 15 0 0 0 0 8 29 0 0 0 % T
% Val: 0 0 0 0 0 8 15 0 36 8 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 8 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _