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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX2 All Species: 12.12
Human Site: S411 Identified Species: 22.22
UniProt: Q13207 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13207 NP_005985.3 712 75066 S411 R G K E P A E S G G D G P F G
Chimpanzee Pan troglodytes XP_511610 735 77439 S434 R G K E P A E S G G D G P F G
Rhesus Macaque Macaca mulatta XP_001106915 952 100638 S651 R G K E P A E S G G D G P F G
Dog Lupus familis XP_534692 710 75612 G409 G G R P R D G G R P D K A S P
Cat Felis silvestris
Mouse Mus musculus Q60707 711 75224 G411 C S K E P T E G G G D G P F S
Rat Rattus norvegicus Q7TST9 743 79316 R429 S R A R D T A R L D K A S P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510378 749 78850 P411 S S L F P P E P A V S G R T R
Chicken Gallus gallus O73718 414 46293 C142 F P P F K V R C T G L D K K A
Frog Xenopus laevis Q6PCL0 691 75547 D401 D S P E S R K D G G S G G D S
Zebra Danio Brachydanio rerio Q7ZTU9 687 75316 S400 Y P D S R K T S D S I F S I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 S654 V E R D G S D S S C S E S V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19691 423 46979 T151 I H P D S P S T G E H W M S K
Sea Urchin Strong. purpuratus NP_001123280 649 70697 R375 V S C K D H E R R M D G K H R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 71.3 51.9 N.A. 94.8 53.1 N.A. 57.4 40.7 71.2 68.8 N.A. 31.6 N.A. 34.2 41.7
Protein Similarity: 100 96.8 72.7 61.7 N.A. 95.9 61.9 N.A. 64.2 46.6 79 76.8 N.A. 39.4 N.A. 44.6 53.3
P-Site Identity: 100 100 100 13.3 N.A. 66.6 0 N.A. 20 6.6 26.6 6.6 N.A. 13.3 N.A. 6.6 20
P-Site Similarity: 100 100 100 20 N.A. 66.6 0 N.A. 20 6.6 33.3 6.6 N.A. 40 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 24 8 0 8 0 0 8 8 0 8 % A
% Cys: 8 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % C
% Asp: 8 0 8 16 16 8 8 8 8 8 47 8 0 8 8 % D
% Glu: 0 8 0 39 0 0 47 0 0 8 0 8 0 0 0 % E
% Phe: 8 0 0 16 0 0 0 0 0 0 0 8 0 31 0 % F
% Gly: 8 31 0 0 8 0 8 16 47 47 0 54 8 0 31 % G
% His: 0 8 0 0 0 8 0 0 0 0 8 0 0 8 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % I
% Lys: 0 0 31 8 8 8 8 0 0 0 8 8 16 8 8 % K
% Leu: 0 0 8 0 0 0 0 0 8 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 16 24 8 39 16 0 8 0 8 0 0 31 8 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 24 8 16 8 16 8 8 16 16 0 0 0 8 0 24 % R
% Ser: 16 31 0 8 16 8 8 39 8 8 24 0 24 16 16 % S
% Thr: 0 0 0 0 0 16 8 8 8 0 0 0 0 8 0 % T
% Val: 16 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _