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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA3B All Species: 7.27
Human Site: S718 Identified Species: 17.78
UniProt: Q13214 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13214 NP_001005914.1 749 83122 S718 R P Q P A L Q S L P L E S R R
Chimpanzee Pan troglodytes XP_001149891 666 74198 L636 P Q P A L Q S L P L E S R R K
Rhesus Macaque Macaca mulatta XP_001102869 749 83324 S718 R P Q P A L Q S L P P E S R R
Dog Lupus familis XP_541878 740 81746 R710 G K E A T G W R G R P D P G G
Cat Felis silvestris
Mouse Mus musculus Q62177 748 82876 S717 R P Q P G H H S V A A D S R R
Rat Rattus norvegicus Q63548 772 88790 Q733 V W K R D R K Q R R Q R P G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506000 839 96323 Q800 V W K R D R K Q R R Q R P G N
Chicken Gallus gallus Q90607 772 88849 Q733 V W K R D R K Q R R Q R P A N
Frog Xenopus laevis NP_001079324 774 89301 Q735 V W K R D R K Q R R Q K N G N
Zebra Danio Brachydanio rerio Q9W686 778 88886 Q726 V W K R E R K Q R R Q K A N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.9 96.4 80.1 N.A. 85.9 51 N.A. 48.2 51.1 49.6 50.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87 97.3 83.9 N.A. 89.5 67 N.A. 63.1 66.9 67.1 66.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 0 N.A. 53.3 0 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 93.3 13.3 N.A. 66.6 13.3 N.A. 13.3 13.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 20 0 0 0 0 10 10 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 40 0 0 0 0 0 0 20 0 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 10 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 10 10 0 0 10 0 0 0 0 40 10 % G
% His: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 50 0 0 0 50 0 0 0 0 20 0 0 10 % K
% Leu: 0 0 0 0 10 20 0 10 20 10 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 30 % N
% Pro: 10 30 10 30 0 0 0 0 10 20 20 0 40 0 0 % P
% Gln: 0 10 30 0 0 10 20 50 0 0 50 0 0 0 0 % Q
% Arg: 30 0 0 50 0 50 0 10 50 60 0 30 10 40 30 % R
% Ser: 0 0 0 0 0 0 10 30 0 0 0 10 30 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 50 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 50 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _