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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC8
All Species:
8.79
Human Site:
Y319
Identified Species:
27.62
UniProt:
Q13216
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13216
NP_000073.1
396
44055
Y319
Y
G
S
T
I
A
V
Y
T
V
Y
S
G
E
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082072
281
31247
A205
H
D
Y
I
L
A
T
A
S
A
D
S
R
V
K
Dog
Lupus familis
XP_544353
396
44021
Y319
Y
G
S
T
I
A
V
Y
T
I
Y
S
G
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFD5
397
43670
Y319
H
G
S
T
I
A
V
Y
A
V
H
S
G
E
R
Rat
Rattus norvegicus
NP_001101120
284
31314
V208
S
T
I
A
M
Y
A
V
Y
S
G
E
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320030
449
49423
M326
L
K
I
T
E
D
G
M
Y
L
L
S
A
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_174105
450
49635
D323
T
G
L
K
A
T
N
D
G
M
Y
L
L
S
A
Baker's Yeast
Sacchar. cerevisiae
Q12021
506
58212
K415
D
L
S
R
I
K
Y
K
K
R
V
S
R
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
70.4
94.4
N.A.
89.6
65.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
70.9
97.9
N.A.
95.4
68.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
40
100
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
28
N.A.
N.A.
33.1
20.1
N.A.
Protein Similarity:
46.9
N.A.
N.A.
51.3
39.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
13
50
13
13
13
13
0
0
13
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
0
0
0
13
0
13
0
0
13
0
0
0
0
% D
% Glu:
0
0
0
0
13
0
0
0
0
0
0
13
0
38
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
13
0
13
0
13
0
38
13
0
% G
% His:
25
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
25
13
50
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
13
0
13
0
13
0
13
13
0
0
0
0
0
13
% K
% Leu:
13
13
13
0
13
0
0
0
0
13
13
13
13
13
13
% L
% Met:
0
0
0
0
13
0
0
13
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% Q
% Arg:
0
0
0
13
0
0
0
0
0
13
0
0
38
13
13
% R
% Ser:
13
0
50
0
0
0
0
0
13
13
0
75
0
13
13
% S
% Thr:
13
13
0
50
0
13
13
0
25
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
38
13
0
25
13
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
13
0
0
13
13
38
25
0
38
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _