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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA
All Species:
9.09
Human Site:
S1259
Identified Species:
33.33
UniProt:
Q13219
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13219
NP_002572.2
1627
180973
S1259
R
D
D
E
L
I
K
S
Q
T
G
P
S
V
T
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
R1438
A
S
S
G
Q
Y
I
R
P
M
Q
K
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
V1214
N
N
P
L
I
I
P
V
V
H
D
L
S
Q
P
Dog
Lupus familis
XP_538813
1502
167461
Q1152
S
E
G
K
W
N
K
Q
V
A
C
E
P
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
S1256
R
D
D
E
L
I
K
S
Q
V
G
P
S
I
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415522
1603
178826
S1235
R
D
D
D
L
S
K
S
Q
T
E
S
S
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
Y1240
K
V
Q
C
M
S
G
Y
R
P
T
K
P
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
86.1
84.8
N.A.
91.2
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
60.1
87.8
88.4
N.A.
95.7
N.A.
N.A.
N.A.
87
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
0
13.3
13.3
N.A.
86.6
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
26.6
26.6
N.A.
93.3
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
0
% C
% Asp:
0
43
43
15
0
0
0
0
0
0
15
0
0
0
15
% D
% Glu:
0
15
0
29
0
0
0
0
0
0
15
15
15
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
15
0
0
15
0
0
0
29
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
43
15
0
0
0
0
0
0
58
0
% I
% Lys:
15
0
0
15
0
0
58
0
0
0
0
29
0
0
0
% K
% Leu:
0
0
0
15
43
0
0
0
0
0
0
15
0
0
15
% L
% Met:
0
0
0
0
15
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
15
15
0
0
0
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
0
0
15
0
15
15
0
29
29
0
15
% P
% Gln:
0
0
15
0
15
0
0
15
43
0
15
0
0
15
0
% Q
% Arg:
43
0
0
0
0
0
0
15
15
0
0
0
0
0
0
% R
% Ser:
15
15
15
0
0
29
0
43
0
0
0
15
58
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
29
15
0
0
0
43
% T
% Val:
0
15
0
0
0
0
0
15
29
15
0
0
0
29
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _