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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA
All Species:
11.21
Human Site:
S145
Identified Species:
41.11
UniProt:
Q13219
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13219
NP_002572.2
1627
180973
S145
T
G
L
Y
D
K
C
S
Y
I
S
R
D
R
G
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
S313
A
G
V
F
D
N
C
S
H
T
V
S
D
K
G
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
A124
E
E
A
K
K
V
E
A
P
R
L
P
K
L
A
Dog
Lupus familis
XP_538813
1502
167461
V86
G
R
L
M
K
L
Y
V
N
G
A
Q
V
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
S142
T
G
L
Y
D
K
C
S
Y
T
S
R
D
R
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415522
1603
178826
S115
A
G
L
Y
D
K
C
S
Y
T
S
R
D
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
K162
A
E
L
S
D
K
C
K
A
S
N
I
V
W
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
86.1
84.8
N.A.
91.2
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
60.1
87.8
88.4
N.A.
95.7
N.A.
N.A.
N.A.
87
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
40
0
6.6
N.A.
93.3
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
66.6
6.6
20
N.A.
93.3
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
15
0
0
0
0
15
15
0
15
0
0
15
15
% A
% Cys:
0
0
0
0
0
0
72
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
72
0
0
0
0
0
0
0
58
0
0
% D
% Glu:
15
29
0
0
0
0
15
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
58
0
0
0
0
0
0
0
15
0
0
0
0
72
% G
% His:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
15
0
0
0
% I
% Lys:
0
0
0
15
29
58
0
15
0
0
0
0
15
15
0
% K
% Leu:
0
0
72
0
0
15
0
0
0
0
15
0
0
15
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
0
15
0
15
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
15
0
43
0
43
0
% R
% Ser:
0
0
0
15
0
0
0
58
0
15
43
15
0
0
0
% S
% Thr:
29
0
0
0
0
0
0
0
0
43
0
0
0
0
15
% T
% Val:
0
0
15
0
0
15
0
15
0
0
15
0
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% W
% Tyr:
0
0
0
43
0
0
15
0
43
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _