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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA
All Species:
3.94
Human Site:
S58
Identified Species:
14.44
UniProt:
Q13219
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13219
NP_002572.2
1627
180973
S58
A
A
R
G
R
R
A
S
P
P
P
P
P
P
P
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
N77
V
Y
P
S
R
A
G
N
Y
L
R
P
Y
P
V
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
A42
S
S
Q
E
R
S
G
A
A
R
K
I
R
A
L
Dog
Lupus familis
XP_538813
1502
167461
C18
K
R
R
L
Y
D
K
C
S
Y
T
S
R
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
S58
A
A
R
G
R
R
A
S
P
P
P
P
P
G
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415522
1603
178826
E41
R
R
S
T
A
G
L
E
P
G
H
V
P
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
D81
S
E
K
L
Q
R
E
D
H
S
R
Y
P
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
86.1
84.8
N.A.
91.2
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
60.1
87.8
88.4
N.A.
95.7
N.A.
N.A.
N.A.
87
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
20
6.6
6.6
N.A.
86.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
33.3
6.6
N.A.
86.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
29
0
0
15
15
29
15
15
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
15
0
0
0
0
0
15
0
% D
% Glu:
0
15
0
15
0
0
15
15
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
29
0
15
29
0
0
15
0
0
0
15
15
% G
% His:
0
0
0
0
0
0
0
0
15
0
15
0
0
0
15
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% I
% Lys:
15
0
15
0
0
0
15
0
0
0
15
0
0
0
0
% K
% Leu:
0
0
0
29
0
0
15
0
0
15
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
0
0
0
0
43
29
29
43
58
29
15
% P
% Gln:
0
0
15
0
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
29
43
0
58
43
0
0
0
15
29
0
29
29
29
% R
% Ser:
29
15
15
15
0
15
0
29
15
15
0
15
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
0
15
0
0
0
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
15
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
15
0
0
0
15
15
0
15
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _