KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPPA
All Species:
9.39
Human Site:
Y1381
Identified Species:
34.44
UniProt:
Q13219
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13219
NP_002572.2
1627
180973
Y1381
K
Y
K
C
K
P
G
Y
H
V
P
G
S
S
R
Chimpanzee
Pan troglodytes
XP_514020
1791
198653
Y1554
D
V
G
T
I
C
K
Y
E
C
K
P
G
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001095160
1573
175281
V1333
Q
M
G
P
S
V
T
V
T
C
T
E
G
K
W
Dog
Lupus familis
XP_538813
1502
167461
S1265
V
P
G
S
S
R
K
S
K
K
R
A
F
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4K8
1624
181300
Y1378
K
Y
K
C
K
P
G
Y
H
V
P
G
S
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415522
1603
178826
Y1357
K
Y
K
C
K
P
G
Y
H
V
P
G
S
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795597
1601
177169
R1357
V
G
S
T
C
K
F
R
C
K
A
G
F
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
86.1
84.8
N.A.
91.2
N.A.
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.3
Protein Similarity:
100
60.1
87.8
88.4
N.A.
95.7
N.A.
N.A.
N.A.
87
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
6.6
0
0
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
6.6
0
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
15
0
0
0
% A
% Cys:
0
0
0
43
15
15
0
0
15
29
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
0
0
29
0
0
% F
% Gly:
0
15
43
0
0
0
43
0
0
0
0
58
29
0
0
% G
% His:
0
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
43
0
43
0
43
15
29
0
15
29
15
0
0
29
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
0
15
0
43
0
0
0
0
43
15
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
15
0
0
15
0
0
0
43
% R
% Ser:
0
0
15
15
29
0
0
15
0
0
0
0
43
43
15
% S
% Thr:
0
0
0
29
0
0
15
0
15
0
15
0
0
15
15
% T
% Val:
29
15
0
0
0
15
0
15
0
43
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% W
% Tyr:
0
43
0
0
0
0
0
58
0
0
0
0
0
15
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _