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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME3
All Species:
46.67
Human Site:
S142
Identified Species:
85.56
UniProt:
Q13232
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13232
NP_002504.2
169
19015
S142
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
Chimpanzee
Pan troglodytes
XP_523261
167
18836
S140
H
G
S
D
S
V
E
S
A
R
R
E
I
A
L
Rhesus Macaque
Macaca mulatta
XP_001096144
240
26905
S213
H
G
S
D
S
V
E
S
A
E
K
E
I
S
L
Dog
Lupus familis
XP_853834
237
25800
S177
H
G
S
D
L
V
E
S
A
R
R
E
I
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV85
169
19081
S142
H
G
S
D
S
V
E
S
A
H
R
E
I
A
L
Rat
Rattus norvegicus
Q05982
152
17174
S125
H
G
S
D
S
V
E
S
A
E
K
E
I
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515701
267
30034
S240
H
G
S
D
S
V
K
S
A
E
K
E
I
G
L
Chicken
Gallus gallus
O57535
153
17269
S126
H
G
S
D
S
V
E
S
A
Q
K
E
I
S
L
Frog
Xenopus laevis
P70010
154
17471
S126
H
G
S
D
S
V
E
S
A
N
K
E
I
A
L
Zebra Danio
Brachydanio rerio
NP_571003
169
19324
S142
H
G
S
D
S
V
E
S
A
A
R
E
I
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08879
153
17151
S126
H
G
S
D
A
V
E
S
A
E
K
E
I
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36010
153
17148
S126
H
G
S
D
S
V
D
S
A
E
R
E
I
N
L
Red Bread Mold
Neurospora crassa
Q9UUY8
152
16882
N125
H
G
S
D
S
V
E
N
A
K
K
E
I
A
L
Conservation
Percent
Protein Identity:
100
94.6
46.6
59.4
N.A.
88.7
60.9
N.A.
41.2
61.5
59.1
72.7
N.A.
60.9
N.A.
N.A.
N.A.
Protein Similarity:
100
94.6
60
64.1
N.A.
93.4
79.8
N.A.
54.6
78.6
78.6
85.8
N.A.
73.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
93.3
N.A.
93.3
80
N.A.
73.3
80
86.6
86.6
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
100
93.3
93.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
53.2
50.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
72.7
69.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
80
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
100
8
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
85
0
0
39
0
100
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
100
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
54
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
24
47
0
0
0
0
% R
% Ser:
0
0
100
0
85
0
0
93
0
0
0
0
0
31
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _