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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NME3 All Species: 19.7
Human Site: Y78 Identified Species: 36.11
UniProt: Q13232 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13232 NP_002504.2 169 19015 Y78 E L R E R P F Y G R L V K Y M
Chimpanzee Pan troglodytes XP_523261 167 18836 E62 L K L V Q A S E E L L R E H Y
Rhesus Macaque Macaca mulatta XP_001096144 240 26905 F149 D L K D R P F F A G L V K Y M
Dog Lupus familis XP_853834 237 25800 Y82 G L R E R P F Y G G L V D Y M
Cat Felis silvestris
Mouse Mus musculus Q9WV85 169 19081 Y78 E L R E K P F Y S R L V K Y M
Rat Rattus norvegicus Q05982 152 17174 F61 D L K D R P F F S G L V K Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515701 267 30034 F176 D L K D R P F F P G L V K Y M
Chicken Gallus gallus O57535 153 17269 Y62 D L K D R P F Y P G L V K Y M
Frog Xenopus laevis P70010 154 17471 Y62 D L K D R P F Y P G L V E Y M
Zebra Danio Brachydanio rerio NP_571003 169 19324 Y78 E L R E K P F Y N G L V K Y M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08879 153 17151 F62 D L S A R P F F P G L V N Y M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36010 153 17148 F62 E H V G K P F F P K M V S F M
Red Bread Mold Neurospora crassa Q9UUY8 152 16882 F61 D L N T K P F F A G L I K Y M
Conservation
Percent
Protein Identity: 100 94.6 46.6 59.4 N.A. 88.7 60.9 N.A. 41.2 61.5 59.1 72.7 N.A. 60.9 N.A. N.A. N.A.
Protein Similarity: 100 94.6 60 64.1 N.A. 93.4 79.8 N.A. 54.6 78.6 78.6 85.8 N.A. 73.9 N.A. N.A. N.A.
P-Site Identity: 100 6.6 60 80 N.A. 86.6 60 N.A. 60 66.6 60 80 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 86.6 80 N.A. 93.3 86.6 N.A. 86.6 86.6 86.6 86.6 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 53.2 50.8
Protein Similarity: N.A. N.A. N.A. N.A. 72.7 69.2
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 16 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 0 39 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 31 0 0 31 0 0 0 8 8 0 0 0 16 0 0 % E
% Phe: 0 0 0 0 0 0 93 47 0 0 0 0 0 8 0 % F
% Gly: 8 0 0 8 0 0 0 0 16 70 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 39 0 31 0 0 0 0 8 0 0 62 0 0 % K
% Leu: 8 85 8 0 0 0 0 0 0 8 93 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 93 % M
% Asn: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 93 0 0 39 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 31 0 62 0 0 0 0 16 0 8 0 0 0 % R
% Ser: 0 0 8 0 0 0 8 0 16 0 0 0 8 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 8 0 0 0 0 0 0 0 85 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 0 0 0 0 0 85 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _