KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K1
All Species:
14.55
Human Site:
S427
Identified Species:
45.71
UniProt:
Q13233
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13233
NP_005912.1
1512
164470
S427
T
L
S
S
S
S
T
S
T
S
S
S
E
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535240
1523
166495
S443
T
L
S
S
S
S
T
S
T
S
S
S
E
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P53349
1493
161270
S422
T
L
S
S
S
S
T
S
T
S
S
S
E
N
S
Rat
Rattus norvegicus
Q62925
1493
161297
S417
T
L
S
S
S
S
T
S
T
S
S
S
E
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506733
1342
147790
S352
P
S
P
V
D
S
P
S
V
L
R
T
V
Q
Q
Chicken
Gallus gallus
XP_424734
1346
148749
Q356
S
S
V
L
H
V
V
Q
Q
Q
T
Q
Q
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693316
840
91458
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795174
1154
127402
N164
L
L
T
Q
S
G
P
N
S
F
L
I
G
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.9
N.A.
89.9
89.2
N.A.
77.3
77
N.A.
40.3
N.A.
N.A.
N.A.
N.A.
33.8
Protein Similarity:
100
N.A.
N.A.
94.1
N.A.
92.9
92.1
N.A.
82.1
81.4
N.A.
45.8
N.A.
N.A.
N.A.
N.A.
50.3
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
0
0
0
0
13
13
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
63
0
13
0
0
0
0
0
13
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
0
50
0
% N
% Pro:
13
0
13
0
0
0
25
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
13
13
13
0
13
13
25
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% R
% Ser:
13
25
50
50
63
63
0
63
13
50
50
50
0
0
63
% S
% Thr:
50
0
13
0
0
0
50
0
50
0
13
13
0
0
0
% T
% Val:
0
0
13
13
0
13
13
0
13
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _