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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K1
All Species:
13.64
Human Site:
S626
Identified Species:
42.86
UniProt:
Q13233
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13233
NP_005912.1
1512
164470
S626
T
S
G
S
S
Q
T
S
I
S
G
D
V
V
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535240
1523
166495
S643
S
S
G
S
S
Q
T
S
I
S
G
D
V
V
E
Cat
Felis silvestris
Mouse
Mus musculus
P53349
1493
161270
S622
A
S
G
S
S
Q
P
S
I
S
G
D
V
V
E
Rat
Rattus norvegicus
Q62925
1493
161297
S617
A
S
G
S
S
Q
P
S
I
S
G
D
V
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506733
1342
147790
A533
I
L
V
K
C
A
D
A
N
S
R
T
S
Q
L
Chicken
Gallus gallus
XP_424734
1346
148749
S537
V
K
C
A
D
A
N
S
R
T
S
Q
L
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693316
840
91458
C31
V
E
T
I
L
V
K
C
A
D
A
N
S
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795174
1154
127402
E345
D
C
A
H
E
N
Q
E
A
G
A
A
S
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.9
N.A.
89.9
89.2
N.A.
77.3
77
N.A.
40.3
N.A.
N.A.
N.A.
N.A.
33.8
Protein Similarity:
100
N.A.
N.A.
94.1
N.A.
92.9
92.1
N.A.
82.1
81.4
N.A.
45.8
N.A.
N.A.
N.A.
N.A.
50.3
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
13.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
13
13
0
25
0
13
25
0
25
13
0
0
0
% A
% Cys:
0
13
13
0
13
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
13
0
13
0
0
13
0
50
0
0
0
% D
% Glu:
0
13
0
0
13
0
0
13
0
0
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
50
0
0
0
0
0
0
13
50
0
0
0
0
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
13
0
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
13
0
13
0
0
13
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
0
13
0
0
0
0
0
0
0
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
13
0
13
0
0
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
13
0
0
0
0
13
0
13
0
% Q
% Arg:
0
0
0
0
0
0
0
0
13
0
13
0
0
13
0
% R
% Ser:
13
50
0
50
50
0
0
63
0
63
13
0
38
25
0
% S
% Thr:
13
0
13
0
0
0
25
0
0
13
0
13
0
0
25
% T
% Val:
25
0
13
0
0
13
0
0
0
0
0
0
50
50
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _