Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKG2 All Species: 27.58
Human Site: S143 Identified Species: 55.15
UniProt: Q13237 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13237 NP_006250.1 762 87432 S143 L N K P P E F S F E K A R V R
Chimpanzee Pan troglodytes XP_517194 773 88573 S143 L N K P P E F S F E K A R V R
Rhesus Macaque Macaca mulatta XP_001084948 865 99274 S213 L N K P P E F S F E K A R V R
Dog Lupus familis XP_544949 762 87274 S143 L N K P P E F S F E K A R V R
Cat Felis silvestris
Mouse Mus musculus Q61410 762 87066 S143 L N K P P E F S F E K A R V R
Rat Rattus norvegicus Q64595 762 87163 S143 L N K P P E F S F E K A R V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085599 783 89666 S165 G G D H Q R F S L E K A C V R
Zebra Danio Brachydanio rerio NP_001098749 768 87435 Y150 S S G I P K F Y F E S A R V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03042 768 86740 F170 I P K Y E K D F S D K Q Q I K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O76360 780 86723 E173 S A E P T N F E N K P A T L Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SL76 1094 121370 A450 V R H D L S R A R I R A I E N
Baker's Yeast Sacchar. cerevisiae P05986 398 45959
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.6 87.7 96.7 N.A. 96 96.3 N.A. N.A. N.A. 70.7 69.5 N.A. 45.4 N.A. 45 N.A.
Protein Similarity: 100 93.2 87.9 98.6 N.A. 98.6 99.3 N.A. N.A. N.A. 82.7 83.8 N.A. 64.9 N.A. 64.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 46.6 46.6 N.A. 13.3 N.A. 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 46.6 60 N.A. 53.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.6 22 N.A.
Protein Similarity: N.A. N.A. N.A. 38 35.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 0 84 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 9 9 0 0 9 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 9 0 9 50 0 9 0 67 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 75 9 59 0 0 0 0 0 0 % F
% Gly: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 9 0 0 0 0 0 9 0 0 9 9 0 % I
% Lys: 0 0 59 0 0 17 0 0 0 9 67 0 0 0 9 % K
% Leu: 50 0 0 0 9 0 0 0 9 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 50 0 0 0 9 0 0 9 0 0 0 0 0 9 % N
% Pro: 0 9 0 59 59 0 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 9 9 0 9 % Q
% Arg: 0 9 0 0 0 9 9 0 9 0 9 0 59 0 59 % R
% Ser: 17 9 0 0 0 9 0 59 9 0 9 0 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _