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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG2
All Species:
27.58
Human Site:
S143
Identified Species:
55.15
UniProt:
Q13237
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13237
NP_006250.1
762
87432
S143
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Chimpanzee
Pan troglodytes
XP_517194
773
88573
S143
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Rhesus Macaque
Macaca mulatta
XP_001084948
865
99274
S213
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Dog
Lupus familis
XP_544949
762
87274
S143
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61410
762
87066
S143
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Rat
Rattus norvegicus
Q64595
762
87163
S143
L
N
K
P
P
E
F
S
F
E
K
A
R
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085599
783
89666
S165
G
G
D
H
Q
R
F
S
L
E
K
A
C
V
R
Zebra Danio
Brachydanio rerio
NP_001098749
768
87435
Y150
S
S
G
I
P
K
F
Y
F
E
S
A
R
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03042
768
86740
F170
I
P
K
Y
E
K
D
F
S
D
K
Q
Q
I
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76360
780
86723
E173
S
A
E
P
T
N
F
E
N
K
P
A
T
L
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL76
1094
121370
A450
V
R
H
D
L
S
R
A
R
I
R
A
I
E
N
Baker's Yeast
Sacchar. cerevisiae
P05986
398
45959
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
87.7
96.7
N.A.
96
96.3
N.A.
N.A.
N.A.
70.7
69.5
N.A.
45.4
N.A.
45
N.A.
Protein Similarity:
100
93.2
87.9
98.6
N.A.
98.6
99.3
N.A.
N.A.
N.A.
82.7
83.8
N.A.
64.9
N.A.
64.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
46.6
46.6
N.A.
13.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
46.6
60
N.A.
53.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38
35.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
0
84
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
9
0
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
50
0
9
0
67
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
75
9
59
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
0
0
9
0
0
9
9
0
% I
% Lys:
0
0
59
0
0
17
0
0
0
9
67
0
0
0
9
% K
% Leu:
50
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
50
0
0
0
9
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
9
0
59
59
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
9
9
0
9
% Q
% Arg:
0
9
0
0
0
9
9
0
9
0
9
0
59
0
59
% R
% Ser:
17
9
0
0
0
9
0
59
9
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _