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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG2
All Species:
17.27
Human Site:
S18
Identified Species:
34.55
UniProt:
Q13237
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13237
NP_006250.1
762
87432
S18
S
K
H
P
D
G
H
S
G
N
L
T
T
D
A
Chimpanzee
Pan troglodytes
XP_517194
773
88573
S18
S
K
H
P
D
G
H
S
G
N
L
T
T
D
A
Rhesus Macaque
Macaca mulatta
XP_001084948
865
99274
S88
S
K
H
P
D
G
H
S
G
N
L
T
T
D
A
Dog
Lupus familis
XP_544949
762
87274
P18
P
K
H
P
D
G
H
P
G
N
L
S
T
H
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61410
762
87066
S18
A
K
H
P
D
G
H
S
G
N
L
S
N
E
A
Rat
Rattus norvegicus
Q64595
762
87163
S18
S
K
H
P
D
G
Q
S
G
N
L
S
N
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085599
783
89666
L18
P
K
Q
P
D
G
Q
L
V
N
F
S
I
N
S
Zebra Danio
Brachydanio rerio
NP_001098749
768
87435
E25
A
K
S
K
N
N
G
E
S
S
L
V
P
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03042
768
86740
D21
I
V
S
N
L
T
K
D
V
Q
A
L
R
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76360
780
86723
A26
S
G
G
A
G
G
G
A
P
G
G
G
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL76
1094
121370
V49
A
V
E
E
D
N
P
V
F
N
F
S
S
D
A
Baker's Yeast
Sacchar. cerevisiae
P05986
398
45959
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
87.7
96.7
N.A.
96
96.3
N.A.
N.A.
N.A.
70.7
69.5
N.A.
45.4
N.A.
45
N.A.
Protein Similarity:
100
93.2
87.9
98.6
N.A.
98.6
99.3
N.A.
N.A.
N.A.
82.7
83.8
N.A.
64.9
N.A.
64.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
N.A.
N.A.
33.3
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
86.6
N.A.
N.A.
N.A.
53.3
33.3
N.A.
6.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38
35.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
9
0
0
0
9
0
0
9
0
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
0
0
9
0
0
0
0
0
34
0
% D
% Glu:
0
0
9
9
0
0
0
9
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% F
% Gly:
0
9
9
0
9
67
17
0
50
9
9
9
9
9
9
% G
% His:
0
0
50
0
0
0
42
0
0
0
0
0
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
67
0
9
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
9
0
0
59
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
9
17
0
0
0
67
0
0
17
9
0
% N
% Pro:
17
0
0
59
0
0
9
9
9
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
0
17
0
0
9
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
42
0
17
0
0
0
0
42
9
9
0
42
9
0
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
25
34
0
0
% T
% Val:
0
17
0
0
0
0
0
9
17
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _