KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG2
All Species:
30
Human Site:
S500
Identified Species:
60
UniProt:
Q13237
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13237
NP_006250.1
762
87432
S500
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Chimpanzee
Pan troglodytes
XP_517194
773
88573
K520
A
M
K
C
I
R
K
K
H
I
V
D
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001084948
865
99274
S603
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Dog
Lupus familis
XP_544949
762
87274
S500
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61410
762
87066
S500
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Rat
Rattus norvegicus
Q64595
762
87163
S500
K
Q
Q
E
H
V
Y
S
E
K
R
I
L
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085599
783
89666
S521
M
Q
Q
E
H
I
H
S
E
K
N
I
L
K
E
Zebra Danio
Brachydanio rerio
NP_001098749
768
87435
S506
R
Q
E
E
H
I
Y
S
E
R
R
I
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03042
768
86740
S506
K
Q
E
E
H
I
F
S
E
R
H
I
M
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76360
780
86723
A517
R
Q
Q
E
H
I
F
A
E
R
N
I
M
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL76
1094
121370
K829
G
K
E
A
Q
V
L
K
E
R
N
L
M
K
N
Baker's Yeast
Sacchar. cerevisiae
P05986
398
45959
Q156
I
R
M
W
G
T
F
Q
D
S
Q
Q
V
F
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
87.7
96.7
N.A.
96
96.3
N.A.
N.A.
N.A.
70.7
69.5
N.A.
45.4
N.A.
45
N.A.
Protein Similarity:
100
93.2
87.9
98.6
N.A.
98.6
99.3
N.A.
N.A.
N.A.
82.7
83.8
N.A.
64.9
N.A.
64.2
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
N.A.
66.6
66.6
N.A.
46.6
N.A.
46.6
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
93.3
N.A.
80
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.6
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38
35.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
0
25
75
0
0
0
0
84
0
0
0
0
42
67
% E
% Phe:
0
0
0
0
0
0
25
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
75
0
9
0
9
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
9
34
0
0
0
9
0
75
0
0
0
% I
% Lys:
50
9
9
0
0
0
9
17
0
50
0
0
0
25
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
9
59
17
0
% L
% Met:
9
9
9
0
0
0
0
0
0
0
0
0
25
9
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
75
59
0
9
0
0
9
0
0
9
9
0
0
9
% Q
% Arg:
17
9
0
0
0
9
0
0
0
34
50
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
9
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
50
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _