Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS5 All Species: 4.85
Human Site: S180 Identified Species: 7.62
UniProt: Q13243 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13243 NP_001034554.1 272 31264 S180 K I K L I E G S K R H S R S R
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S130 R R R R R S R S R S R S R S R
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 K176 K I R L V E D K P G S R R R R
Dog Lupus familis XP_867104 261 29928 K167 A I E K L S G K E I N G R K I
Cat Felis silvestris
Mouse Mus musculus O35326 270 30926 I178 T G E K S K L I E G S K R H R
Rat Rattus norvegicus Q09167 269 30873 I177 N G R K I K L I E G S K R H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517768 256 29451 K164 E I N G R K I K L I E G S K R
Chicken Gallus gallus Q5ZML3 257 28042 V160 F R D G T G V V E F V R K E D
Frog Xenopus laevis NP_001079543 261 29430 A167 S Y T D M K S A L D K L D G V
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 D154 C Y A D V F R D G T G V V E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R192 R I H L V E D R R G G R S G G
Honey Bee Apis mellifera XP_391860 342 39488 K196 R I R L I E D K R R G R R S R
Nematode Worm Caenorhab. elegans Q23121 312 35023 S214 R S R S N S R S R S R S R S R
Sea Urchin Strong. purpuratus XP_798746 311 35431 R217 S R S H S R S R S R S R R R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 G207 D S R S P S R G R S Y S K S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 42.2 95.2 N.A. 89.3 97.7 N.A. 92.2 38.9 67.2 46.3 N.A. 50.5 52.6 50.3 58.8
Protein Similarity: 100 42.2 48.7 95.2 N.A. 91.1 97.7 N.A. 93 51.8 79 56.2 N.A. 59.5 64.3 65 71
P-Site Identity: 100 33.3 40 20 N.A. 13.3 20 N.A. 13.3 0 0 0 N.A. 20 53.3 33.3 13.3
P-Site Similarity: 100 53.3 53.3 46.6 N.A. 33.3 40 N.A. 26.6 13.3 20 6.6 N.A. 40 73.3 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 14 0 0 20 7 0 7 0 0 7 0 7 % D
% Glu: 7 0 14 0 0 27 0 0 27 0 7 0 0 14 0 % E
% Phe: 7 0 0 0 0 7 0 0 0 7 0 0 0 0 7 % F
% Gly: 0 14 0 14 0 7 14 7 7 27 20 14 0 14 7 % G
% His: 0 0 7 7 0 0 0 0 0 0 7 0 0 14 0 % H
% Ile: 0 40 0 0 20 0 7 14 0 14 0 0 0 0 7 % I
% Lys: 14 0 7 20 0 27 0 27 7 0 7 14 14 14 0 % K
% Leu: 0 0 0 27 7 0 14 0 14 0 0 7 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 7 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 27 20 40 7 14 7 27 14 34 20 14 34 60 14 60 % R
% Ser: 14 14 7 14 14 27 14 20 7 20 27 27 14 34 7 % S
% Thr: 7 0 7 0 7 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 20 0 7 7 0 0 7 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 14 0 0 0 0 0 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _