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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS5 All Species: 8.48
Human Site: S184 Identified Species: 13.33
UniProt: Q13243 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13243 NP_001034554.1 272 31264 S184 I E G S K R H S R S R S R S R
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S134 R S R S R S R S R S R S R S R
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 R180 V E D K P G S R R R R S Y S R
Dog Lupus familis XP_867104 261 29928 G171 L S G K E I N G R K I K L I E
Cat Felis silvestris
Mouse Mus musculus O35326 270 30926 K182 S K L I E G S K R H R S R S R
Rat Rattus norvegicus Q09167 269 30873 K181 I K L I E G S K R H R S R S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517768 256 29451 G168 R K I K L I E G S K R H R S R
Chicken Gallus gallus Q5ZML3 257 28042 R164 T G V V E F V R K E D M T Y A
Frog Xenopus laevis NP_001079543 261 29430 L171 M K S A L D K L D G V E L S G
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 V158 V F R D G T G V V E F V R K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R196 V E D R R G G R S G G G G G S
Honey Bee Apis mellifera XP_391860 342 39488 R200 I E D K R R G R R S R S S S S
Nematode Worm Caenorhab. elegans Q23121 312 35023 S218 N S R S R S R S R S R D R R R
Sea Urchin Strong. purpuratus XP_798746 311 35431 R221 S R S R S R S R R R S R S P R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S211 P S R G R S Y S K S R S R S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 42.2 95.2 N.A. 89.3 97.7 N.A. 92.2 38.9 67.2 46.3 N.A. 50.5 52.6 50.3 58.8
Protein Similarity: 100 42.2 48.7 95.2 N.A. 91.1 97.7 N.A. 93 51.8 79 56.2 N.A. 59.5 64.3 65 71
P-Site Identity: 100 60 40 13.3 N.A. 40 46.6 N.A. 26.6 0 6.6 6.6 N.A. 6.6 53.3 46.6 20
P-Site Similarity: 100 66.6 46.6 33.3 N.A. 53.3 60 N.A. 33.3 13.3 26.6 13.3 N.A. 20 60 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 7 0 7 0 0 7 0 7 7 0 0 0 % D
% Glu: 0 27 0 0 27 0 7 0 0 14 0 7 0 0 14 % E
% Phe: 0 7 0 0 0 7 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 14 7 7 27 20 14 0 14 7 7 7 7 7 % G
% His: 0 0 0 0 0 0 7 0 0 14 0 7 0 0 0 % H
% Ile: 20 0 7 14 0 14 0 0 0 0 7 0 0 7 0 % I
% Lys: 0 27 0 27 7 0 7 14 14 14 0 7 0 7 0 % K
% Leu: 7 0 14 0 14 0 0 7 0 0 0 0 14 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 7 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 7 27 14 34 20 14 34 60 14 60 7 54 7 60 % R
% Ser: 14 27 14 20 7 20 27 27 14 34 7 47 14 60 14 % S
% Thr: 7 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % T
% Val: 20 0 7 7 0 0 7 7 7 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _