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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS5 All Species: 40
Human Site: S223 Identified Species: 62.86
UniProt: Q13243 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13243 NP_001034554.1 272 31264 S223 R S R S R S R S R S K S R S V
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S173 A R R S K S K S S S V S R S R
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 S219 S K K E K S R S P S K D K S R
Dog Lupus familis XP_867104 261 29928 S210 R S R S R S R S R S K S R S V
Cat Felis silvestris
Mouse Mus musculus O35326 270 30926 S221 R S R S R S R S R S K S R S G
Rat Rattus norvegicus Q09167 269 30873 S220 R S R S R S R S R S K S R S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517768 256 29451 S207 Y S R S R S R S R S R S K S R
Chicken Gallus gallus Q5ZML3 257 28042 G203 G P R S P S Y G R S R S R S V
Frog Xenopus laevis NP_001079543 261 29430 S210 R S R S K S K S R G S S K S V
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 R197 R V K V D G P R S P S Y G R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S235 S S H S R S K S R S R S K S R
Honey Bee Apis mellifera XP_391860 342 39488 S239 R S R S R R S S R S K S R A H
Nematode Worm Caenorhab. elegans Q23121 312 35023 S257 K S K S R S R S R S R S A D N
Sea Urchin Strong. purpuratus XP_798746 311 35431 K260 K S P R K S P K R S R S R S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S250 R S P A K S T S R S P G P R S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 42.2 95.2 N.A. 89.3 97.7 N.A. 92.2 38.9 67.2 46.3 N.A. 50.5 52.6 50.3 58.8
Protein Similarity: 100 42.2 48.7 95.2 N.A. 91.1 97.7 N.A. 93 51.8 79 56.2 N.A. 59.5 64.3 65 71
P-Site Identity: 100 53.3 40 100 N.A. 93.3 93.3 N.A. 73.3 60 66.6 6.6 N.A. 60 73.3 60 46.6
P-Site Similarity: 100 66.6 60 100 N.A. 93.3 93.3 N.A. 86.6 66.6 86.6 13.3 N.A. 80 80 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 0 0 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 0 0 0 7 0 7 0 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 7 0 7 0 7 0 7 7 0 14 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 14 7 20 0 34 0 20 7 0 0 40 0 27 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 14 0 7 0 14 0 7 7 7 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 54 7 60 7 54 7 47 7 80 0 34 0 54 14 27 % R
% Ser: 14 74 0 74 0 87 7 80 14 87 14 80 0 74 14 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 7 0 0 0 0 0 0 7 0 0 0 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _