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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS5 All Species: 38.79
Human Site: S227 Identified Species: 60.95
UniProt: Q13243 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13243 NP_001034554.1 272 31264 S227 R S R S R S K S R S V S R S P
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S177 K S K S S S V S R S R S R S R
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 D223 K S R S P S K D K S R S R S R
Dog Lupus familis XP_867104 261 29928 S214 R S R S R S K S R S V S R S P
Cat Felis silvestris
Mouse Mus musculus O35326 270 30926 S225 R S R S R S K S R S G S R S P
Rat Rattus norvegicus Q09167 269 30873 S224 R S R S R S K S R S G S R S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517768 256 29451 S211 R S R S R S R S K S R S V S R
Chicken Gallus gallus Q5ZML3 257 28042 S207 P S Y G R S R S R S V V V A E
Frog Xenopus laevis NP_001079543 261 29430 S214 K S K S R G S S K S V S R S R
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 Y201 D G P R S P S Y G R S R S R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S239 R S K S R S R S K S R G G R S
Honey Bee Apis mellifera XP_391860 342 39488 S243 R R S S R S K S R A H T K S K
Nematode Worm Caenorhab. elegans Q23121 312 35023 S261 R S R S R S R S A D N R K S R
Sea Urchin Strong. purpuratus XP_798746 311 35431 S264 K S P K R S R S R S L S P M K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 G254 K S T S R S P G P R S K S R S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 42.2 95.2 N.A. 89.3 97.7 N.A. 92.2 38.9 67.2 46.3 N.A. 50.5 52.6 50.3 58.8
Protein Similarity: 100 42.2 48.7 95.2 N.A. 91.1 97.7 N.A. 93 51.8 79 56.2 N.A. 59.5 64.3 65 71
P-Site Identity: 100 60 60 100 N.A. 93.3 93.3 N.A. 66.6 46.6 60 0 N.A. 46.6 53.3 53.3 46.6
P-Site Similarity: 100 73.3 73.3 100 N.A. 93.3 93.3 N.A. 80 60 80 0 N.A. 66.6 73.3 66.6 66.6
Percent
Protein Identity: N.A. N.A. N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 7 0 7 0 7 7 0 14 7 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 34 0 20 7 0 0 40 0 27 0 0 7 14 0 14 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 7 0 14 0 7 7 7 0 7 0 0 0 7 0 27 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 54 7 47 7 80 0 34 0 54 14 27 14 47 20 34 % R
% Ser: 0 87 7 80 14 87 14 80 0 74 14 60 14 67 20 % S
% Thr: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 0 0 0 0 0 0 7 0 0 0 27 7 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _