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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS5 All Species: 18.79
Human Site: S245 Identified Species: 29.52
UniProt: Q13243 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13243 NP_001034554.1 272 31264 S245 K S Q K R G S S S R S K S P A
Chimpanzee Pan troglodytes Q5R1W5 221 25469 V195 R S R S P P P V S K R E P K S
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 D241 K S R S K S K D Q A E E K I Q
Dog Lupus familis XP_867104 261 29928 S232 K S Q K R G S S S R S K S P A
Cat Felis silvestris
Mouse Mus musculus O35326 270 30926 S243 K S Q K R G S S S R S K S P A
Rat Rattus norvegicus Q09167 269 30873 S242 K S Q K R G S S S R S K S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517768 256 29451 G229 P E K S Q K R G S S S R S K S
Chicken Gallus gallus Q5ZML3 257 28042 V225 G A T A E A A V I P Q E E A E
Frog Xenopus laevis NP_001079543 261 29430 S232 R T P E R K Y S Q K N S P A E
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 R219 S R S R S N S R S R S Y S P R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R257 S P V K S R S R S R S R S N K
Honey Bee Apis mellifera XP_391860 342 39488 S261 K S K S P E R S R T R S K S K
Nematode Worm Caenorhab. elegans Q23121 312 35023 R279 R S P K K V D R S P S P P R G
Sea Urchin Strong. purpuratus XP_798746 311 35431 S282 R S C S R S K S P R N S R S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 R272 R R S R S R S R S P L P S V Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.7 42.2 95.2 N.A. 89.3 97.7 N.A. 92.2 38.9 67.2 46.3 N.A. 50.5 52.6 50.3 58.8
Protein Similarity: 100 42.2 48.7 95.2 N.A. 91.1 97.7 N.A. 93 51.8 79 56.2 N.A. 59.5 64.3 65 71
P-Site Identity: 100 13.3 13.3 100 N.A. 100 100 N.A. 20 0 13.3 40 N.A. 40 20 26.6 26.6
P-Site Similarity: 100 46.6 33.3 100 N.A. 100 100 N.A. 46.6 20 46.6 46.6 N.A. 46.6 26.6 40 40
Percent
Protein Identity: N.A. N.A. N.A. 40.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 56.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 7 7 0 0 7 0 0 0 14 27 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 7 7 7 0 0 0 0 7 20 7 0 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 27 0 7 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % I
% Lys: 40 0 14 40 14 14 14 0 0 14 0 27 14 14 14 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 14 0 0 7 0 % N
% Pro: 7 7 14 0 14 7 7 0 7 20 0 14 20 34 7 % P
% Gln: 0 0 27 0 7 0 0 0 14 0 7 0 0 0 14 % Q
% Arg: 34 14 14 14 40 14 14 27 7 47 14 14 7 7 7 % R
% Ser: 14 60 14 34 20 14 47 47 67 7 54 20 54 14 14 % S
% Thr: 0 7 7 0 0 0 0 0 0 7 0 0 0 0 0 % T
% Val: 0 0 7 0 0 7 0 14 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _