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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS5
All Species:
20.61
Human Site:
S250
Identified Species:
32.38
UniProt:
Q13243
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13243
NP_001034554.1
272
31264
S250
G
S
S
S
R
S
K
S
P
A
S
V
D
R
Q
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
P200
P
P
V
S
K
R
E
P
K
S
R
S
R
S
K
Rhesus Macaque
Macaca mulatta
XP_001113510
464
53241
K246
S
K
D
Q
A
E
E
K
I
Q
N
N
D
N
A
Dog
Lupus familis
XP_867104
261
29928
S237
G
S
S
S
R
S
K
S
P
A
S
V
D
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35326
270
30926
S248
G
S
S
S
R
S
K
S
P
A
S
V
D
R
Q
Rat
Rattus norvegicus
Q09167
269
30873
S247
G
S
S
S
R
S
K
S
P
A
S
V
D
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517768
256
29451
S234
K
R
G
S
S
S
R
S
K
S
P
A
S
V
G
Chicken
Gallus gallus
Q5ZML3
257
28042
E230
A
A
V
I
P
Q
E
E
A
E
D
L
H
A
T
Frog
Xenopus laevis
NP_001079543
261
29430
P237
K
Y
S
Q
K
N
S
P
A
E
P
A
Q
G
S
Zebra Danio
Brachydanio rerio
Q6NYA0
245
27457
S224
N
S
R
S
R
S
Y
S
P
R
R
S
R
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26686
376
42795
S262
R
S
R
S
R
S
R
S
N
K
S
R
D
V
S
Honey Bee
Apis mellifera
XP_391860
342
39488
K266
E
R
S
R
T
R
S
K
S
K
S
R
D
R
S
Nematode Worm
Caenorhab. elegans
Q23121
312
35023
P284
V
D
R
S
P
S
P
P
R
G
S
R
S
P
S
Sea Urchin
Strong. purpuratus
XP_798746
311
35431
R287
S
K
S
P
R
N
S
R
S
P
S
P
I
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
S277
R
S
R
S
P
L
P
S
V
Q
K
E
G
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.7
42.2
95.2
N.A.
89.3
97.7
N.A.
92.2
38.9
67.2
46.3
N.A.
50.5
52.6
50.3
58.8
Protein Similarity:
100
42.2
48.7
95.2
N.A.
91.1
97.7
N.A.
93
51.8
79
56.2
N.A.
59.5
64.3
65
71
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
20
0
6.6
40
N.A.
46.6
26.6
20
26.6
P-Site Similarity:
100
33.3
20
100
N.A.
100
100
N.A.
33.3
20
20
40
N.A.
53.3
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
14
27
0
14
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
0
0
7
0
47
0
0
% D
% Glu:
7
0
0
0
0
7
20
7
0
14
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
27
0
7
0
0
0
0
0
0
7
0
0
7
14
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
14
14
0
0
14
0
27
14
14
14
7
0
0
0
14
% K
% Leu:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
14
0
0
7
0
7
7
0
7
0
% N
% Pro:
7
7
0
7
20
0
14
20
34
7
14
7
0
7
0
% P
% Gln:
0
0
0
14
0
7
0
0
0
14
0
0
7
0
34
% Q
% Arg:
14
14
27
7
47
14
14
7
7
7
14
20
14
34
0
% R
% Ser:
14
47
47
67
7
54
20
54
14
14
54
14
14
14
34
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% T
% Val:
7
0
14
0
0
0
0
0
7
0
0
27
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _