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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS6 All Species: 5.15
Human Site: S196 Identified Species: 8.72
UniProt: Q13247 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13247 NP_006266.2 344 39587 S196 R S Y S G S R S R S R S R R R
Chimpanzee Pan troglodytes Q5R1W5 221 25469 A74 D A E D A M D A M D G A V L D
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 S296 R G R S Q E K S L R Q S R S R
Dog Lupus familis XP_534422 287 32895 A140 Q A G E V T Y A D A H K E R T
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 S325 R A R S Q E K S R S Q E K S L
Rat Rattus norvegicus Q09167 269 30873 Q122 L S S R V S W Q D L K D F M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512981 401 44678 P232 R S R S A D G P R G E S Q D K
Chicken Gallus gallus
Frog Xenopus laevis NP_001079647 667 76917 N513 T S K Q E R S N S R S K S K R
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 G97 S G R G G G R G G G G G G G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 R207 G G G S G R G R S R S S S S R
Honey Bee Apis mellifera XP_391860 342 39488 D195 R R I R L I E D K R R G R R S
Nematode Worm Caenorhab. elegans Q23120 281 32403 K134 D I K D H I R K L G I E P T Y
Sea Urchin Strong. purpuratus XP_798746 311 35431 H164 F A D A H K Q H K N E G I V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 G156 Q V Y R D A R G T T G V V D Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 56.9 68.9 N.A. 56 54.9 N.A. 58.5 N.A. 43.4 22.6 N.A. 56.1 61 45.9 60.4
Protein Similarity: 100 43 63.7 72.9 N.A. 61.9 62.2 N.A. 67 N.A. 47 32.5 N.A. 66.7 72.3 59 70.3
P-Site Identity: 100 0 40 6.6 N.A. 33.3 20 N.A. 33.3 N.A. 13.3 13.3 N.A. 26.6 26.6 6.6 0
P-Site Similarity: 100 20 53.3 40 N.A. 60 26.6 N.A. 46.6 N.A. 26.6 13.3 N.A. 26.6 33.3 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. 43.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 57.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 0 8 15 8 0 15 0 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 8 15 8 8 8 8 15 8 0 8 0 15 8 % D
% Glu: 0 0 8 8 8 15 8 0 0 0 15 15 8 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 22 15 8 22 8 15 15 8 22 22 22 8 8 0 % G
% His: 0 0 0 0 15 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 0 8 8 0 0 15 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 15 0 0 8 15 8 15 0 8 15 8 8 8 % K
% Leu: 8 0 0 0 8 0 0 0 15 8 0 0 0 8 8 % L
% Met: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % P
% Gln: 15 0 0 8 15 0 8 8 0 0 15 0 8 0 0 % Q
% Arg: 36 8 29 22 0 15 29 8 22 29 15 0 22 22 36 % R
% Ser: 8 29 8 36 0 15 8 22 15 15 15 29 15 22 8 % S
% Thr: 8 0 0 0 0 8 0 0 8 8 0 0 0 8 8 % T
% Val: 0 8 0 0 15 0 0 0 0 0 0 8 15 8 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 8 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _