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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS6
All Species:
12.12
Human Site:
S274
Identified Species:
20.51
UniProt:
Q13247
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13247
NP_006266.2
344
39587
S274
D
E
Y
E
K
S
R
S
R
S
R
S
R
S
P
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
R152
S
R
S
K
S
R
S
R
T
R
S
R
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001113510
464
53241
S374
E
D
T
D
R
S
Q
S
R
S
P
S
R
S
M
Dog
Lupus familis
XP_534422
287
32895
R218
S
I
S
K
S
R
S
R
S
R
S
K
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE97
489
55961
S403
T
D
H
S
R
S
P
S
R
S
V
S
K
E
R
Rat
Rattus norvegicus
Q09167
269
30873
R200
T
R
S
S
S
R
S
R
S
R
S
R
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512981
401
44678
R310
S
K
D
K
R
K
G
R
K
R
S
R
E
R
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079647
667
76917
S591
G
K
R
E
R
S
R
S
R
S
K
G
K
R
G
Zebra Danio
Brachydanio rerio
Q6NYA0
245
27457
D175
T
Y
A
V
R
K
L
D
N
T
K
F
R
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26686
376
42795
K285
R
T
R
S
R
S
P
K
R
E
R
D
S
R
S
Honey Bee
Apis mellifera
XP_391860
342
39488
S273
K
S
K
S
R
D
R
S
K
S
K
S
K
S
K
Nematode Worm
Caenorhab. elegans
Q23120
281
32403
R212
R
S
R
S
P
P
A
R
R
R
S
P
G
S
D
Sea Urchin
Strong. purpuratus
XP_798746
311
35431
R242
S
R
S
R
S
R
S
R
S
R
S
R
K
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
R234
S
R
S
R
S
R
S
R
S
P
K
A
K
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.8
56.9
68.9
N.A.
56
54.9
N.A.
58.5
N.A.
43.4
22.6
N.A.
56.1
61
45.9
60.4
Protein Similarity:
100
43
63.7
72.9
N.A.
61.9
62.2
N.A.
67
N.A.
47
32.5
N.A.
66.7
72.3
59
70.3
P-Site Identity:
100
0
46.6
0
N.A.
33.3
0
N.A.
0
N.A.
40
13.3
N.A.
20
33.3
13.3
6.6
P-Site Similarity:
100
6.6
80
6.6
N.A.
60
0
N.A.
26.6
N.A.
66.6
33.3
N.A.
26.6
60
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
8
8
0
8
0
8
0
0
0
8
0
0
8
% D
% Glu:
8
8
0
15
0
0
0
0
0
8
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
0
8
15
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
15
8
22
8
15
0
8
15
0
29
8
36
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
15
0
0
8
8
8
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
15
29
22
15
50
36
22
50
43
43
15
29
22
43
22
% R
% Ser:
36
15
36
36
36
36
36
36
29
36
43
29
22
50
36
% S
% Thr:
22
8
8
0
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _