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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS6 All Species: 6.67
Human Site: S291 Identified Species: 11.28
UniProt: Q13247 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13247 NP_006266.2 344 39587 S291 N G K G D I K S K S R S R S Q
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S169 K S R S A R R S K S K S S S V
Rhesus Macaque Macaca mulatta XP_001113510 464 53241 E391 E R E H A K S E S S Q R E G R
Dog Lupus familis XP_534422 287 32895 R235 R S K G R K S R S K S K S K P
Cat Felis silvestris
Mouse Mus musculus Q8VE97 489 55961 R420 A K A E S G Q R G S R A E G E
Rat Rattus norvegicus Q09167 269 30873 R217 S Y S R S R S R S R S R S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512981 401 44678 G327 R S R S P S K G E K N K K R S
Chicken Gallus gallus
Frog Xenopus laevis NP_001079647 667 76917 K608 E G R P N A K K A R S T R S R
Zebra Danio Brachydanio rerio Q6NYA0 245 27457 K192 E T A Y I R V K V D G P R S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S302 R S V S K R E S R S R S R S K
Honey Bee Apis mellifera XP_391860 342 39488 K290 S R S R S R S K A E R S K S R
Nematode Worm Caenorhab. elegans Q23120 281 32403 S229 D R K S R S A S P K K R S D K
Sea Urchin Strong. purpuratus XP_798746 311 35431 P259 S K S P R K S P K R S R S R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 R251 S P A K S T S R S P G P R S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.8 56.9 68.9 N.A. 56 54.9 N.A. 58.5 N.A. 43.4 22.6 N.A. 56.1 61 45.9 60.4
Protein Similarity: 100 43 63.7 72.9 N.A. 61.9 62.2 N.A. 67 N.A. 47 32.5 N.A. 66.7 72.3 59 70.3
P-Site Identity: 100 33.3 6.6 13.3 N.A. 13.3 0 N.A. 6.6 N.A. 26.6 13.3 N.A. 40 20 13.3 6.6
P-Site Similarity: 100 53.3 26.6 13.3 N.A. 33.3 6.6 N.A. 26.6 N.A. 53.3 13.3 N.A. 60 40 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 43.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 57.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 22 0 15 8 8 0 15 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 22 0 8 8 0 0 8 8 8 8 0 0 15 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 15 0 8 0 8 8 0 15 0 0 15 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 15 22 8 8 22 22 22 22 22 15 15 15 15 22 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 8 0 15 8 0 0 8 8 8 0 15 0 0 15 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 8 % Q
% Arg: 22 22 22 15 22 36 8 29 8 22 29 29 36 15 22 % R
% Ser: 29 29 22 29 29 15 43 29 29 36 29 29 36 50 22 % S
% Thr: 0 8 0 0 0 8 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 8 0 0 0 8 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _