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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS6
All Species:
11.21
Human Site:
S295
Identified Species:
18.97
UniProt:
Q13247
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13247
NP_006266.2
344
39587
S295
D
I
K
S
K
S
R
S
R
S
Q
S
R
S
N
Chimpanzee
Pan troglodytes
Q5R1W5
221
25469
S173
A
R
R
S
K
S
K
S
S
S
V
S
R
S
R
Rhesus Macaque
Macaca mulatta
XP_001113510
464
53241
R395
A
K
S
E
S
S
Q
R
E
G
R
G
E
S
E
Dog
Lupus familis
XP_534422
287
32895
K239
R
K
S
R
S
K
S
K
S
K
P
K
S
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE97
489
55961
A424
S
G
Q
R
G
S
R
A
E
G
E
S
E
A
P
Rat
Rattus norvegicus
Q09167
269
30873
R221
S
R
S
R
S
R
S
R
S
K
S
R
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512981
401
44678
K331
P
S
K
G
E
K
N
K
K
R
S
K
R
D
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079647
667
76917
T612
N
A
K
K
A
R
S
T
R
S
R
S
G
S
H
Zebra Danio
Brachydanio rerio
Q6NYA0
245
27457
P196
I
R
V
K
V
D
G
P
R
S
P
S
Y
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26686
376
42795
S306
K
R
E
S
R
S
R
S
R
S
K
S
I
H
R
Honey Bee
Apis mellifera
XP_391860
342
39488
S294
S
R
S
K
A
E
R
S
K
S
R
S
Q
S
K
Nematode Worm
Caenorhab. elegans
Q23120
281
32403
R233
R
S
A
S
P
K
K
R
S
D
K
R
A
R
S
Sea Urchin
Strong. purpuratus
XP_798746
311
35431
R263
R
K
S
P
K
R
S
R
S
R
S
L
S
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22315
303
33711
P255
S
T
S
R
S
P
G
P
R
S
K
S
R
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.8
56.9
68.9
N.A.
56
54.9
N.A.
58.5
N.A.
43.4
22.6
N.A.
56.1
61
45.9
60.4
Protein Similarity:
100
43
63.7
72.9
N.A.
61.9
62.2
N.A.
67
N.A.
47
32.5
N.A.
66.7
72.3
59
70.3
P-Site Identity:
100
53.3
13.3
0
N.A.
20
0
N.A.
13.3
N.A.
33.3
20
N.A.
46.6
33.3
6.6
6.6
P-Site Similarity:
100
66.6
26.6
0
N.A.
46.6
6.6
N.A.
26.6
N.A.
60
20
N.A.
66.6
53.3
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
0
15
0
0
8
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
8
0
0
0
15
0
% D
% Glu:
0
0
8
8
8
8
0
0
15
0
8
0
15
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
0
15
0
0
15
0
8
8
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
22
22
22
22
22
15
15
15
15
22
15
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
8
8
0
15
0
0
15
0
0
8
15
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% Q
% Arg:
22
36
8
29
8
22
29
29
36
15
22
15
29
8
29
% R
% Ser:
29
15
43
29
29
36
29
29
36
50
22
58
22
43
15
% S
% Thr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _