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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L1
All Species:
42.12
Human Site:
Y38
Identified Species:
61.78
UniProt:
Q13257
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13257
NP_002349.1
205
23510
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Chimpanzee
Pan troglodytes
XP_517581
196
22483
I31
F
S
F
G
I
N
S
I
L
Y
Q
R
G
I
Y
Rhesus Macaque
Macaca mulatta
XP_001084989
205
23614
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Dog
Lupus familis
XP_533278
205
23552
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B5
205
23580
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Rat
Rattus norvegicus
NP_001100064
205
23520
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513397
205
23385
Y38
I
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
Chicken
Gallus gallus
XP_420629
206
23693
Y39
I
L
Y
Q
R
G
I
Y
P
P
E
T
F
T
R
Frog
Xenopus laevis
NP_001080741
203
23361
P38
L
Y
Q
R
G
I
Y
P
S
E
T
F
T
R
I
Zebra Danio
Brachydanio rerio
NP_001017739
202
23158
A37
Y
Q
R
G
I
Y
P
A
E
T
F
T
R
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023563
203
23510
P38
L
Y
Q
R
A
L
Y
P
S
D
S
F
K
R
E
Sea Urchin
Strong. purpuratus
XP_001178696
206
23671
Y39
L
L
Y
Q
R
G
I
Y
P
A
E
T
F
T
R
Poplar Tree
Populus trichocarpa
XP_002311730
207
23536
Y38
I
L
Y
N
R
G
V
Y
P
E
E
S
F
V
K
Maize
Zea mays
Q9XFH3
208
23486
Y38
I
L
Y
N
R
A
V
Y
P
E
E
S
F
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
Y39
I
L
Y
N
R
A
V
Y
P
E
E
S
F
V
K
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
V31
S
I
L
Y
Q
R
G
V
Y
P
A
E
D
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
97.5
97.5
N.A.
94.1
94.1
N.A.
93.6
86.8
80.4
74.1
N.A.
N.A.
N.A.
50.2
65
Protein Similarity:
100
95.6
97.5
98.5
N.A.
96
97
N.A.
97.5
92.2
89.2
86.8
N.A.
N.A.
N.A.
72.1
77.6
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
93.3
0
6.6
N.A.
N.A.
N.A.
0
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
93.3
13.3
13.3
N.A.
N.A.
N.A.
13.3
100
Percent
Protein Identity:
46.8
43.7
N.A.
44
41.4
N.A.
Protein Similarity:
67.6
65.8
N.A.
65.5
59.5
N.A.
P-Site Identity:
60
53.3
N.A.
53.3
0
N.A.
P-Site Similarity:
80
80
N.A.
73.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
13
0
7
0
7
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
25
69
7
0
0
7
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
7
13
69
7
0
% F
% Gly:
0
0
0
13
7
57
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
63
7
0
0
13
7
50
7
0
0
0
0
0
7
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
19
% K
% Leu:
19
69
7
0
0
7
0
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
13
69
13
0
0
0
0
0
% P
% Gln:
0
7
13
50
7
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
7
13
69
7
0
0
0
0
0
7
7
13
50
% R
% Ser:
7
7
0
0
0
0
7
0
13
38
7
19
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
7
57
7
50
7
% T
% Val:
0
0
0
0
0
0
19
7
0
0
0
0
0
19
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
69
7
0
7
13
69
7
7
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _