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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX3
All Species:
41.82
Human Site:
S118
Identified Species:
70.77
UniProt:
Q13277
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13277
NP_004168.1
289
33155
S118
A
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Chimpanzee
Pan troglodytes
XP_001135446
289
33209
S118
A
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Rhesus Macaque
Macaca mulatta
XP_001089614
290
33308
S118
A
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Dog
Lupus familis
XP_534637
338
37747
T167
V
D
L
R
I
R
R
T
Q
H
S
V
L
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64704
289
33225
S118
A
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Rat
Rattus norvegicus
Q08849
289
33239
S118
A
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517955
391
43905
I147
P
A
I
F
T
S
G
I
I
D
S
Q
I
S
K
Chicken
Gallus gallus
XP_001233551
316
35842
T146
A
D
L
R
I
R
K
T
Q
H
S
T
L
S
R
Frog
Xenopus laevis
NP_001086322
286
32704
S116
T
D
L
R
I
R
K
S
Q
H
S
V
L
S
R
Zebra Danio
Brachydanio rerio
NP_956837
288
32381
S116
A
D
M
R
I
R
K
S
Q
H
A
V
L
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
R119
S
S
A
D
L
R
I
R
K
T
Q
H
S
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
T119
A
D
L
R
I
R
K
T
Q
H
S
T
L
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64791
303
34450
T123
P
G
S
S
T
D
R
T
R
T
S
V
V
S
G
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
N121
N
K
Q
A
Q
A
E
N
C
R
Q
K
F
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
52.9
N.A.
97.9
97.9
N.A.
55.7
57.9
71.2
75.4
N.A.
57.3
N.A.
55.3
N.A.
Protein Similarity:
100
99.3
99.3
70.1
N.A.
98.9
98.9
N.A.
60.8
74.3
85.8
87.5
N.A.
78
N.A.
74.2
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
13.3
86.6
93.3
86.6
N.A.
6.6
N.A.
86.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
33.3
93.3
93.3
100
N.A.
33.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
8
8
8
0
8
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
72
0
8
0
8
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
72
0
8
0
0
0
% H
% Ile:
0
0
8
0
72
0
8
8
8
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
0
65
0
8
0
0
8
0
0
15
% K
% Leu:
0
0
65
0
8
0
0
0
0
0
0
0
72
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
72
0
15
8
0
0
0
% Q
% Arg:
0
0
0
72
0
79
15
8
8
8
0
0
0
0
72
% R
% Ser:
8
8
8
8
0
8
0
50
0
0
79
0
8
86
0
% S
% Thr:
8
0
0
0
15
0
0
29
0
15
0
15
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
65
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _