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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX3
All Species:
22.73
Human Site:
S206
Identified Species:
38.46
UniProt:
Q13277
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13277
NP_004168.1
289
33155
S206
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Chimpanzee
Pan troglodytes
XP_001135446
289
33209
S206
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Rhesus Macaque
Macaca mulatta
XP_001089614
290
33308
S206
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Dog
Lupus familis
XP_534637
338
37747
E255
H
K
D
I
M
K
L
E
T
S
I
R
E
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q64704
289
33225
S206
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Rat
Rattus norvegicus
Q08849
289
33239
S206
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517955
391
43905
V235
R
K
M
I
I
I
I
V
I
V
V
V
S
L
C
Chicken
Gallus gallus
XP_001233551
316
35842
E234
H
S
E
I
I
K
L
E
N
S
I
R
E
L
H
Frog
Xenopus laevis
NP_001086322
286
32704
E204
H
R
D
I
V
R
L
E
S
S
L
K
E
L
H
Zebra Danio
Brachydanio rerio
NP_956837
288
32381
S204
K
D
I
V
R
L
E
S
S
I
K
E
L
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
K207
A
R
H
Q
D
I
M
K
L
E
T
S
I
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
E207
H
N
D
I
M
K
L
E
S
S
I
R
E
L
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64791
303
34450
D211
S
E
I
Q
E
R
H
D
A
V
K
E
I
E
K
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
K209
Q
E
L
L
K
L
E
K
T
M
A
E
L
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
52.9
N.A.
97.9
97.9
N.A.
55.7
57.9
71.2
75.4
N.A.
57.3
N.A.
55.3
N.A.
Protein Similarity:
100
99.3
99.3
70.1
N.A.
98.9
98.9
N.A.
60.8
74.3
85.8
87.5
N.A.
78
N.A.
74.2
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
0
6.6
100
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
33.3
13.3
20
100
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
43
22
0
8
0
0
8
0
0
0
0
0
0
43
% D
% Glu:
0
15
8
0
8
0
50
29
0
8
0
58
29
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
29
0
8
0
0
0
8
0
0
0
0
0
0
43
29
% H
% Ile:
0
0
50
36
15
15
8
0
8
43
22
0
15
0
0
% I
% Lys:
43
15
0
0
8
22
0
15
0
0
50
8
0
8
8
% K
% Leu:
0
0
8
8
0
50
29
0
8
0
8
0
50
36
0
% L
% Met:
0
0
8
0
15
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
15
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
15
0
0
43
15
0
0
0
0
0
22
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
43
58
29
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
15
0
8
0
0
8
0
% T
% Val:
0
0
0
43
8
0
0
8
0
15
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _