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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX3
All Species:
36.36
Human Site:
S258
Identified Species:
61.54
UniProt:
Q13277
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13277
NP_004168.1
289
33155
S258
K
K
A
V
K
Y
Q
S
Q
A
R
K
K
L
I
Chimpanzee
Pan troglodytes
XP_001135446
289
33209
S258
K
K
A
V
K
Y
Q
S
Q
A
R
K
K
L
I
Rhesus Macaque
Macaca mulatta
XP_001089614
290
33308
S258
K
K
A
V
K
Y
Q
S
Q
A
R
K
K
L
I
Dog
Lupus familis
XP_534637
338
37747
S308
K
K
A
I
K
Y
H
S
K
A
R
R
K
K
W
Cat
Felis silvestris
Mouse
Mus musculus
Q64704
289
33225
G258
K
R
A
M
K
Y
Q
G
Q
A
R
K
K
L
I
Rat
Rattus norvegicus
Q08849
289
33239
G258
K
R
A
M
K
Y
Q
G
Q
A
R
K
K
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517955
391
43905
T316
L
R
E
L
Q
C
S
T
R
A
P
L
K
P
I
Chicken
Gallus gallus
XP_001233551
316
35842
S287
K
K
A
V
K
Y
Q
S
K
A
R
R
K
K
I
Frog
Xenopus laevis
NP_001086322
286
32704
S257
K
K
A
V
K
F
Q
S
D
A
R
R
K
K
I
Zebra Danio
Brachydanio rerio
NP_956837
288
32381
S256
K
K
A
V
R
Y
Q
S
K
A
R
K
K
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
S262
K
K
A
L
K
Y
Q
S
K
A
R
R
K
K
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
S260
K
K
A
V
Q
Y
Q
S
K
A
R
R
K
K
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64791
303
34450
K270
Q
D
A
R
E
Y
Q
K
S
S
R
K
W
T
C
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
R261
N
K
A
V
K
S
A
R
K
A
R
K
N
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
52.9
N.A.
97.9
97.9
N.A.
55.7
57.9
71.2
75.4
N.A.
57.3
N.A.
55.3
N.A.
Protein Similarity:
100
99.3
99.3
70.1
N.A.
98.9
98.9
N.A.
60.8
74.3
85.8
87.5
N.A.
78
N.A.
74.2
N.A.
P-Site Identity:
100
100
100
60
N.A.
80
80
N.A.
20
80
73.3
80
N.A.
73.3
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
93.3
N.A.
53.3
93.3
86.6
100
N.A.
93.3
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.1
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
93
0
0
0
8
0
0
93
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
86
% I
% Lys:
79
72
0
0
72
0
0
8
43
0
0
58
86
43
0
% K
% Leu:
8
0
0
15
0
0
0
0
0
0
0
8
0
36
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
8
0
0
0
15
0
79
0
36
0
0
0
0
0
0
% Q
% Arg:
0
22
0
8
8
0
0
8
8
0
93
36
0
0
0
% R
% Ser:
0
0
0
0
0
8
8
65
8
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% T
% Val:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
0
0
0
0
0
79
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _