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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLN3
All Species:
4.85
Human Site:
S261
Identified Species:
13.33
UniProt:
Q13286
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13286
NP_000077.1
438
47623
S261
I
R
T
E
A
P
E
S
K
P
G
S
S
S
S
Chimpanzee
Pan troglodytes
XP_523328
352
38227
S186
A
V
I
S
W
W
S
S
G
T
G
G
A
G
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61124
438
47755
S261
I
G
T
E
T
P
E
S
K
P
G
A
S
W
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514486
433
47507
S261
Q
E
L
S
L
N
S
S
P
T
L
S
F
K
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086663
433
47849
Q251
H
Q
P
L
I
A
G
Q
S
H
D
T
T
G
G
Zebra Danio
Brachydanio rerio
NP_001007307
446
49412
L252
N
S
E
E
R
R
A
L
I
E
E
D
T
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394336
415
45964
E243
I
P
R
K
S
F
K
E
K
I
N
L
V
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47040
408
46365
L241
V
P
L
T
T
V
Y
L
F
E
Y
L
I
N
Q
Red Bread Mold
Neurospora crassa
Q7SC45
464
50477
D273
Y
S
S
H
P
T
E
D
A
R
K
D
S
L
A
Conservation
Percent
Protein Identity:
100
78.7
N.A.
N.A.
N.A.
84.9
N.A.
N.A.
74.8
N.A.
57.3
50.6
N.A.
N.A.
40.4
N.A.
N.A.
Protein Similarity:
100
79.2
N.A.
N.A.
N.A.
89.9
N.A.
N.A.
85.1
N.A.
72.8
65.4
N.A.
N.A.
59.8
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
13.3
N.A.
0
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
13.3
N.A.
20
20
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.8
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
42
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
12
12
0
12
0
0
12
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
12
23
0
12
23
% D
% Glu:
0
12
12
34
0
0
34
12
0
23
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
12
0
0
0
12
0
0
% F
% Gly:
0
12
0
0
0
0
12
0
12
0
34
12
0
23
23
% G
% His:
12
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
34
0
12
0
12
0
0
0
12
12
0
0
12
0
0
% I
% Lys:
0
0
0
12
0
0
12
0
34
0
12
0
0
12
0
% K
% Leu:
0
0
23
12
12
0
0
23
0
0
12
23
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
0
0
0
12
0
0
12
0
% N
% Pro:
0
23
12
0
12
23
0
0
12
23
0
0
0
12
0
% P
% Gln:
12
12
0
0
0
0
0
12
0
0
0
0
0
0
12
% Q
% Arg:
0
12
12
0
12
12
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
23
12
23
12
0
23
45
12
0
0
23
34
12
12
% S
% Thr:
0
0
23
12
23
12
0
0
0
23
0
12
23
0
12
% T
% Val:
12
12
0
0
0
12
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
12
12
0
0
0
0
0
0
0
12
0
% W
% Tyr:
12
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _