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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLN3
All Species:
3.94
Human Site:
S270
Identified Species:
10.83
UniProt:
Q13286
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13286
NP_000077.1
438
47623
S270
P
G
S
S
S
S
L
S
L
R
E
R
W
T
V
Chimpanzee
Pan troglodytes
XP_523328
352
38227
G195
T
G
G
A
G
L
L
G
A
L
S
Y
L
G
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61124
438
47755
S270
P
G
A
S
W
D
L
S
L
Q
E
R
W
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514486
433
47507
W270
T
L
S
F
K
D
R
W
S
V
F
K
G
L
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086663
433
47849
F260
H
D
T
T
G
G
V
F
I
L
G
L
S
E
K
Zebra Danio
Brachydanio rerio
NP_001007307
446
49412
E261
E
E
D
T
D
T
D
E
D
S
E
P
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394336
415
45964
L252
I
N
L
V
P
G
L
L
K
Y
M
I
P
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47040
408
46365
V250
E
Y
L
I
N
Q
A
V
A
P
T
L
L
F
P
Red Bread Mold
Neurospora crassa
Q7SC45
464
50477
K282
R
K
D
S
L
A
A
K
I
Q
R
S
K
S
L
Conservation
Percent
Protein Identity:
100
78.7
N.A.
N.A.
N.A.
84.9
N.A.
N.A.
74.8
N.A.
57.3
50.6
N.A.
N.A.
40.4
N.A.
N.A.
Protein Similarity:
100
79.2
N.A.
N.A.
N.A.
89.9
N.A.
N.A.
85.1
N.A.
72.8
65.4
N.A.
N.A.
59.8
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
6.6
N.A.
0
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
20
N.A.
26.6
20
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.8
26.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
42
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
12
23
0
23
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
23
0
12
23
12
0
12
0
0
0
0
0
0
% D
% Glu:
23
12
0
0
0
0
0
12
0
0
34
0
0
12
12
% E
% Phe:
0
0
0
12
0
0
0
12
0
0
12
0
0
12
0
% F
% Gly:
0
34
12
0
23
23
0
12
0
0
12
0
12
12
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
23
0
0
12
0
0
0
% I
% Lys:
0
12
0
0
12
0
0
12
12
0
0
12
12
0
12
% K
% Leu:
0
12
23
0
12
12
45
12
23
23
0
23
23
34
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
0
0
12
0
0
0
0
12
0
12
12
0
12
% P
% Gln:
0
0
0
0
0
12
0
0
0
23
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
12
0
0
12
12
23
0
0
0
% R
% Ser:
0
0
23
34
12
12
0
23
12
12
12
12
12
12
0
% S
% Thr:
23
0
12
23
0
12
0
0
0
0
12
0
0
23
0
% T
% Val:
0
0
0
12
0
0
12
12
0
12
0
0
0
0
23
% V
% Trp:
0
0
0
0
12
0
0
12
0
0
0
0
23
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _