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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKP2
All Species:
8.79
Human Site:
Y128
Identified Species:
19.33
UniProt:
Q13309
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13309
NP_005974.2
424
47761
Y128
S
G
V
C
K
R
W
Y
R
L
A
S
D
E
S
Chimpanzee
Pan troglodytes
XP_001147537
379
42771
L87
V
I
V
R
R
P
K
L
N
R
E
N
F
P
G
Rhesus Macaque
Macaca mulatta
XP_001093834
422
47441
Q126
S
N
V
V
E
D
F
Q
H
L
V
S
D
E
S
Dog
Lupus familis
XP_546346
749
81658
Y453
S
S
V
C
K
R
W
Y
H
L
A
F
D
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0Z3
424
47748
Y128
S
G
V
C
K
R
W
Y
R
L
S
L
D
E
S
Rat
Rattus norvegicus
Q9QZH7
276
30442
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007983
443
49750
H149
S
M
I
C
K
R
W
H
R
L
S
F
D
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036659
499
55071
S183
I
N
Y
F
E
R
L
S
D
E
I
L
L
D
I
Honey Bee
Apis mellifera
XP_395497
484
54314
C192
M
L
V
C
K
R
W
C
Q
I
A
R
D
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780472
456
51238
R141
A
K
V
C
R
R
W
R
R
L
S
Y
D
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49286
360
39891
L69
V
S
L
G
L
T
R
L
S
L
S
W
C
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.3
91.9
52.3
N.A.
86.3
23.5
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
30
27.8
N.A.
31.3
Protein Similarity:
100
89.3
94.5
54.6
N.A.
92.9
36.7
N.A.
N.A.
74.4
N.A.
N.A.
N.A.
50.9
50.6
N.A.
50
P-Site Identity:
100
6.6
46.6
80
N.A.
86.6
0
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
6.6
53.3
N.A.
53.3
P-Site Similarity:
100
20
60
80
N.A.
93.3
0
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
20
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
28
0
0
0
10
% A
% Cys:
0
0
0
55
0
0
0
10
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
0
0
0
64
10
0
% D
% Glu:
0
0
0
0
19
0
0
0
0
10
10
0
0
64
10
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
19
10
0
0
% F
% Gly:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
10
19
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
0
0
0
10
10
0
0
0
10
% I
% Lys:
0
10
0
0
46
0
10
0
0
0
0
0
0
10
10
% K
% Leu:
0
10
10
0
10
0
10
19
0
64
0
19
10
0
0
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
19
64
10
10
37
10
0
10
0
0
0
% R
% Ser:
46
19
0
0
0
0
0
10
10
0
37
19
0
0
46
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
64
10
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
55
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
28
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _