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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPC4 All Species: 19.7
Human Site: S456 Identified Species: 33.33
UniProt: Q13310 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13310 NP_001129126.1 644 70783 S456 M P S A I R Q S G P R P T L R
Chimpanzee Pan troglodytes XP_513344 656 72174 S456 M P S A I R Q S G P R P T L R
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 G240 D A S G K S K G F G F V R Y E
Dog Lupus familis XP_857000 644 70650 S456 M P S A I R Q S G P R P A L R
Cat Felis silvestris
Mouse Mus musculus P29341 636 70624 A457 M P G A I R P A A P R P P F S
Rat Rattus norvegicus Q9EPH8 636 70682 A457 M P G A I R P A A P R P P F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515603 630 69727 S456 M P N A M R Q S G P R P A L R
Chicken Gallus gallus XP_417821 630 69611 S456 M P N A M R Q S G P R P A L R
Frog Xenopus laevis Q6IP09 633 70403 S455 M A G A I R P S A P R P P T F
Zebra Danio Brachydanio rerio NP_958453 637 70651 P458 M P S S L R Q P G P R A N I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21187 634 69907 A446 V Q A G A A A A G G F Q G T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05196 668 73191 M489 G A G P P N F M M P F P L Q R
Baker's Yeast Sacchar. cerevisiae P04147 577 64326 A429 A T A A A A A A A A G M P G Q
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 G542 G Q Y P Y Q Q G G R G G V P P
Conservation
Percent
Protein Identity: 100 96.9 39.2 99.2 N.A. 77 77 N.A. 88.6 89.2 76.4 84.7 N.A. 59.7 N.A. N.A. N.A.
Protein Similarity: 100 97 47.9 99.5 N.A. 85.2 85 N.A. 93.3 93.4 84.6 90.3 N.A. 72.6 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 53.3 53.3 N.A. 80 80 53.3 60 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 60 60 N.A. 93.3 93.3 53.3 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 43.1 45.1 41.3
Protein Similarity: N.A. N.A. N.A. 59.4 59.7 54.3
P-Site Identity: N.A. N.A. N.A. 20 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 20 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 15 65 15 15 15 29 29 8 0 8 22 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 22 0 0 15 8 % F
% Gly: 15 0 29 15 0 0 0 15 58 15 15 8 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 43 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 0 0 0 0 8 36 0 % L
% Met: 65 0 0 0 15 0 0 8 8 0 0 8 0 0 0 % M
% Asn: 0 0 15 0 0 8 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 58 0 15 8 0 22 8 0 72 0 65 29 8 8 % P
% Gln: 0 15 0 0 0 8 50 0 0 0 0 8 0 8 8 % Q
% Arg: 0 0 0 0 0 65 0 0 0 8 65 0 8 0 50 % R
% Ser: 0 0 36 8 0 8 0 43 0 0 0 0 0 0 15 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 15 15 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _