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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R2
All Species:
13.03
Human Site:
Y39
Identified Species:
31.85
UniProt:
Q13319
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13319
NP_003927.1
367
38705
Y39
G
D
E
A
L
G
G
Y
G
A
P
P
V
G
K
Chimpanzee
Pan troglodytes
XP_516099
367
38658
Y39
G
D
E
A
L
G
G
Y
G
A
P
P
V
G
K
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
R12
L
S
L
S
P
S
Y
R
K
A
T
L
F
E
D
Dog
Lupus familis
XP_853120
458
47635
Y127
G
D
E
A
L
G
G
Y
G
A
P
P
A
G
K
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
Y39
G
D
E
A
L
G
G
Y
G
A
P
P
A
G
K
Rat
Rattus norvegicus
P61810
307
34013
R12
L
S
L
S
P
S
Y
R
K
A
T
L
F
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089375
320
35634
P25
D
E
K
K
P
E
A
P
G
V
G
G
G
Y
S
Zebra Danio
Brachydanio rerio
NP_001017569
308
34577
R12
L
S
I
S
P
T
S
R
K
G
G
I
L
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
G30
H
L
F
S
P
G
D
G
G
P
T
F
A
P
Q
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
V41
Y
L
N
N
S
K
N
V
A
S
T
K
E
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
49.5
77.2
N.A.
94.3
48.7
N.A.
N.A.
N.A.
58.3
55.5
N.A.
N.A.
N.A.
31.6
36.5
Protein Similarity:
100
99.7
59.1
77.7
N.A.
94.8
58.5
N.A.
N.A.
N.A.
64.5
64.8
N.A.
N.A.
N.A.
42.5
49.8
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
6.6
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
13.3
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
40
0
0
10
0
10
60
0
0
30
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
40
0
0
0
0
10
0
0
0
0
0
0
10
20
% D
% Glu:
0
10
40
0
0
10
0
0
0
0
0
0
10
20
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
10
20
0
0
% F
% Gly:
40
0
0
0
0
50
40
10
60
10
20
10
10
40
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
10
10
0
10
0
0
30
0
0
10
0
0
40
% K
% Leu:
30
20
20
0
40
0
0
0
0
0
0
20
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
50
0
0
10
0
10
40
40
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% R
% Ser:
0
30
0
40
10
20
10
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
40
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
10
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
20
40
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _