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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SP140
All Species:
6.36
Human Site:
S406
Identified Species:
20
UniProt:
Q13342
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13342
NP_009168.4
867
98223
S406
E
E
R
Q
E
A
S
S
S
L
A
R
R
G
S
Chimpanzee
Pan troglodytes
XP_526052
885
101638
G421
A
P
A
E
A
S
S
G
A
L
R
S
K
H
G
Rhesus Macaque
Macaca mulatta
XP_001112173
866
98023
S344
E
E
P
Q
E
A
S
S
S
L
A
R
C
G
S
Dog
Lupus familis
XP_852450
763
87841
T366
P
E
G
P
E
A
S
T
A
S
S
Q
A
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVK9
445
50122
A54
M
Y
K
E
S
L
E
A
C
Q
N
L
V
P
L
Rat
Rattus norvegicus
Q3KRF1
478
53186
K87
M
L
L
I
L
F
S
K
V
N
L
R
E
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513758
1105
125920
A446
S
I
W
P
W
A
W
A
A
A
L
Q
Q
C
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_683309
1080
124708
V465
T
T
Y
S
A
Q
L
V
S
S
Q
R
Y
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.1
89.7
50.5
N.A.
22.1
21.5
N.A.
22.8
N.A.
N.A.
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.9
93.6
61.9
N.A.
33.3
32.9
N.A.
35.8
N.A.
N.A.
38.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
86.6
26.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
86.6
53.3
N.A.
20
13.3
N.A.
40
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
13
0
25
50
0
25
38
13
25
0
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
0
0
13
25
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
25
38
0
25
38
0
13
0
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
0
13
0
0
0
0
0
25
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
13
0
13
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
13
0
0
0
0
13
0
0
% K
% Leu:
0
13
13
0
13
13
13
0
0
38
25
13
0
0
13
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
13
0
0
0
0
% N
% Pro:
13
13
13
25
0
0
0
0
0
0
0
0
0
13
13
% P
% Gln:
0
0
0
25
0
13
0
0
0
13
13
25
13
0
0
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
13
50
13
0
0
% R
% Ser:
13
0
0
13
13
13
63
25
38
25
13
13
0
0
25
% S
% Thr:
13
13
0
0
0
0
0
13
0
0
0
0
0
13
13
% T
% Val:
0
0
0
0
0
0
0
13
13
0
0
0
13
0
0
% V
% Trp:
0
0
13
0
13
0
13
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
13
0
0
0
0
0
0
0
0
0
13
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _