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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL2
All Species:
33.64
Human Site:
S378
Identified Species:
74
UniProt:
Q13356
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13356
NP_680481.1
520
58823
S378
S
G
P
N
S
N
R
S
Q
F
F
I
T
F
R
Chimpanzee
Pan troglodytes
XP_001168978
520
58777
S378
S
G
P
N
S
N
K
S
Q
F
F
I
T
F
R
Rhesus Macaque
Macaca mulatta
XP_001088432
378
42947
A237
K
V
D
K
L
N
A
A
H
Y
S
T
G
K
V
Dog
Lupus familis
XP_534768
523
59161
S378
S
G
P
N
A
N
K
S
Q
F
F
I
T
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D787
521
59046
S378
S
G
P
N
T
N
K
S
Q
F
F
I
T
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079584
521
59210
S378
T
G
P
N
T
N
K
S
Q
F
F
I
T
F
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611113
517
58940
P373
L
S
M
A
N
S
G
P
N
T
N
G
S
Q
F
Honey Bee
Apis mellifera
XP_623363
521
59810
S378
S
G
P
N
T
N
G
S
Q
F
F
I
T
F
R
Nematode Worm
Caenorhab. elegans
P52012
523
58515
S378
K
G
S
N
T
N
G
S
Q
F
F
I
T
F
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJX0
595
65005
S442
S
G
P
H
T
N
G
S
Q
F
F
V
L
Y
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RXA6
597
65782
S428
K
G
K
N
T
N
S
S
Q
F
F
I
T
Y
R
Conservation
Percent
Protein Identity:
100
99.8
66.9
92.3
N.A.
90.2
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
N.A.
54
57
48.7
N.A.
Protein Similarity:
100
100
68.4
96.5
N.A.
95.9
N.A.
N.A.
N.A.
N.A.
88.8
N.A.
N.A.
73.4
72.9
65.3
N.A.
P-Site Identity:
100
93.3
6.6
86.6
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
0
86.6
73.3
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
100
N.A.
N.A.
20
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.7
N.A.
39.7
Protein Similarity:
N.A.
N.A.
N.A.
59.5
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
82
82
0
0
64
10
% F
% Gly:
0
82
0
0
0
0
37
0
0
0
0
10
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% I
% Lys:
28
0
10
10
0
0
37
0
0
0
0
0
0
10
10
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
73
10
91
0
0
10
0
10
0
0
0
0
% N
% Pro:
0
0
64
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
82
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
73
% R
% Ser:
55
10
10
0
19
10
10
82
0
0
10
0
10
0
0
% S
% Thr:
10
0
0
0
55
0
0
0
0
10
0
10
73
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _