KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL2
All Species:
9.09
Human Site:
S506
Identified Species:
20
UniProt:
Q13356
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13356
NP_680481.1
520
58823
S506
T
S
A
T
V
P
M
S
K
K
K
P
S
R
G
Chimpanzee
Pan troglodytes
XP_001168978
520
58777
S506
T
S
A
T
V
P
M
S
K
K
K
P
S
R
G
Rhesus Macaque
Macaca mulatta
XP_001088432
378
42947
S365
H
T
G
R
G
I
L
S
M
A
N
S
G
P
N
Dog
Lupus familis
XP_534768
523
59161
V506
E
P
S
T
S
T
A
V
P
V
A
K
K
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D787
521
59046
T506
S
T
S
T
A
T
P
T
A
K
K
R
P
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079584
521
59210
S506
D
E
A
G
P
S
T
S
K
K
E
R
V
T
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611113
517
58940
A501
A
P
L
T
S
A
Q
A
A
K
K
K
K
L
A
Honey Bee
Apis mellifera
XP_623363
521
59810
K506
L
N
I
P
S
T
I
K
K
K
K
T
V
T
N
Nematode Worm
Caenorhab. elegans
P52012
523
58515
A506
M
E
D
V
P
L
E
A
A
K
K
T
K
F
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJX0
595
65005
I570
K
G
S
L
D
S
D
I
S
T
I
G
V
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RXA6
597
65782
V556
K
Y
L
D
V
G
A
V
K
K
A
A
T
T
T
Conservation
Percent
Protein Identity:
100
99.8
66.9
92.3
N.A.
90.2
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
N.A.
54
57
48.7
N.A.
Protein Similarity:
100
100
68.4
96.5
N.A.
95.9
N.A.
N.A.
N.A.
N.A.
88.8
N.A.
N.A.
73.4
72.9
65.3
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
20
20
13.3
N.A.
P-Site Similarity:
100
100
20
20
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
26.6
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.7
N.A.
39.7
Protein Similarity:
N.A.
N.A.
N.A.
59.5
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
28
0
10
10
19
19
28
10
19
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
19
0
0
0
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
10
10
10
10
10
0
0
0
0
0
10
10
0
19
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
10
10
0
0
10
0
0
0
0
% I
% Lys:
19
0
0
0
0
0
0
10
46
73
55
19
28
10
10
% K
% Leu:
10
0
19
10
0
10
10
0
0
0
0
0
0
10
0
% L
% Met:
10
0
0
0
0
0
19
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
19
% N
% Pro:
0
19
0
10
19
19
10
0
10
0
0
19
10
10
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
19
0
19
19
% R
% Ser:
10
19
28
0
28
19
0
37
10
0
0
10
19
19
0
% S
% Thr:
19
19
0
46
0
28
10
10
0
10
0
19
10
28
10
% T
% Val:
0
0
0
10
28
0
0
19
0
10
0
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _